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The protective effects of suplhate magnesium and insulin on ischemic brain tissue in rats
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1008-6706.2002.05.005
- Key Word:
- 硫酸镁;胰岛素;缺血脑组织
Abstract： 目的探讨镁与胰岛素对缺血脑组织的保护作用.方法大鼠全脑缺血前后腹腔注射硫酸镁和胰岛素,与对照组比较脑组织含水量、神经细胞计数和形态学观察、超氧化物歧化酶(SOD)和神经原特异性烯醇化酶(NSE).结果观察组海马区正常神经元计数和SOD含量显著高于对照组(P分别＜0.01和0.05),脑组织含水量和NSE含量显著低于对照(P分别＜0.01和0.05).结论硫酸镁和胰岛素对缺血脑组织有肯定的保护作用.
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