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Clinic investigation on treatment for ectopic pregnancy with combination of methotrexate with mifepristone or single methotrexate
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1008-6706.2001.02.003
- Key Word:
- 异位妊娠;氨甲碟呤;米非司酮
Abstract： 目的比较氨甲碟呤联合米非司酮与单用氨甲碟呤治疗异位妊娠的疗效.方法将临床确诊为异位妊娠39例分为A、B两组,A组19例为单一MTX治疗,肌注MTX 50 mg,每人3 d一次,共3次;B组20例为MTX联合米非司酮治疗,MTX的量及给药方法同A组,米非司酮的剂量为50 mg/d,连续3 d.βHCG下降至正常(正常值＜5 IU/L)为治愈,发生腹腔出血而手术治疗者为失败.对两组的成功率、成功病人的住院时间进行统计学处理.结果氨甲碟呤联合米非司酮治疗组20例,18例成功,成功率为90%.而单用氨甲碟呤治疗组19例,13例成功,成功率为64.8%.氨甲碟呤联合米非司酮治疗组的住院时间为25.3±4.8 d,而单用氨甲碟呤治疗组为29.8±3.7 d.经统计学检验,P＜0.05.结论联合治疗可以缩短住院时间,对于异位妊娠治疗有其使用价值.
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