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Research progress in gastrointestinal transportation of cyclodextrin inclusion complex and its mechanism

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Author:
No author available
Journal Title:
Chinese Traditional and Herbal Drugs
Issue:
10
DOI:
No doi available
Key Word:
环糊精;生物利用度;吸收;包合物;胃肠道转运

Abstract: 环糊精包合可提高难溶性药物溶解度,增加挥发性或不稳定性成分的稳定性,提高药物的生物利用度.在文献研究的基础上,综合分析环糊精包合对药物吸收及生物利用度的影响,探讨包合物胃肠道给药后环糊精对包合的客分子药物吸收的影响机制,为进一步阐明包合物中药物在胃肠吸收过程中释放与跨膜转运规律奠定基础.

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