Abstract: Objective To study the active constituents of Physalis alkekengi var. franchetii. Methods The compounds were separated by silica gel and Sephadex LH-20 chromatography method, their structures were, identified on the spectral analyses and physical data. Results Eleven compounds were isolated and i-dentified as β-sitosterol ( I ) , physalin A ( II ) > physalin B ( Ⅲ ), physalin O (Ⅳ ) > physalin L (Ⅴ ), phys-alin M (Ⅵ), daucosterol (Ⅶ), ombuine (Ⅷ)> 5, 4', 5'-trihydroxy-7, 3'-dimethoxy-flavonol (Ⅸ), luteo-lin ( X ), and luteolin-7-O-β-D-glucopyranoside ( Ⅺ ). Conclusion Compound IX is a new compound named physaflavonol.