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Chemical constituents of Acanthopanax gracilistylus

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Author:
No author available
Journal Title:
CHINESE TRADITIONAL AND HERBAL DRUGS
Issue:
3
DOI:
10.3321/j.issn:0253-2670.2004.03.005
Key Word:
细柱五加皮;五加科;化学成分;Acanthopanax gracilistylus W. W. Smith;Araliaceae;chemical constituent

Abstract: Object To study the chemical constituents of Acanthopanax gracilistylus W. W. Smith as the purpose of study continually on plants of Acanthopanax (Decne. et Planch.) Miq. Methods The leaves, roots, and stem barks of A. gracilistylus were extracted with hot MeOH and steam distillation respectively, and then, separated and purified by column chromatographies on Diaion HP-20P, Chromatorex ODS, Sephadex LH-20 and silica gel. All compounds were identified on the basis of chemical and spectral analysis including GC-MS, 1D and 2D NMR, MS and IR, or comparison with the reported data. Results Six compounds were obtained from the roots of A. gracilistylus. They are (-)-pimara-9 (11), 15-dien-19-oic acid (Ⅰ), (-)-kaur-16-en-19-oic acid (Ⅱ), d-sesamin (Ⅲ), stigmasterol (Ⅳ), β-sitosterol (Ⅴ), and eleutheroside B (Ⅵ). Conclusion Compounds Ⅰ, Ⅳ, and Ⅴ are obtained from this plant for the first time.

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