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Chemical constituents from root of Glycyrrhiza uralensis

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Author:
No author available
Journal Title:
CHINESE TRADITIONAL AND HERBAL DRUGS
Issue:
3
DOI:
10.3321/j.issn:0253-2670.2003.03.003
Key Word:
乌拉尔甘草;三萜皂苷;3-O-[β-D-葡萄糖醛酸甲酯-(1→2)-β-D-葡萄糖醛酸]-24-羟基-甘草内酯;Glycyrrhiza uralensis Fisch;triterpenoid saponins;3-O-[β-D-(6-methyl) glucuronopyranosyl (1→2)-D-glucuronopyranosyl]-24-hydroxy-glabrolide

Abstract: Object To investigate the chemical constituents from the roots of Glycyrrhiza uralensis Fisch. Methods The constituents were isolated on normal and reversed silica gel column chromatography and their structures were identified by spectral evidence. Results A new oleanane-type triterpenoid saponin and twelve known compounds, including two triterpenoid saponins, two cumarins and eight flavonoids, were isolated. Conclusion The new compound was elucidated as 3-O-[β-D-(6-methyl) glucuronopyranosyl (1→2)-D-glucuronopyranosyl]-24-hydroxy-glabrolide on the basis of ESI-MS, 1HNMR,13CNMR, HMQC and HMBC spectral evidence.

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