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Studies on chemical constituents of Callicarpa pedunculata
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- Author:
- No author available
- Journal Title:
- CHINESE TRADITIONAL AND HERBAL DRUGS
- Issue:
- 12
- DOI:
- 10.3321/j.issn:0253-2670.2001.12.003
- Key Word:
- 紫株;二萜类化合物;黄酮类化合物
Abstract： 目的研究紫株Callicarpa Pedunculata R.Brown的化学成分.方法利用各种色谱技术进行分离纯化,通过各种理化方法及光谱(IR,MS,1HNMR,13CNMR)分析鉴定其化学结构.结果从紫株全草的氯仿提取物中分离得到10种化合物,分别鉴定为:4个二萜类化合物:14α-羟基-7,15-异松烷二烯-18烷酸(14α-hydroxy-7,15-isopimaradien-18-oic acid,Ⅰ);16α,17-二羟基-3-氧-扁枝杉烷(16α,17-dihydroxy-3-oxo-phyllocladane,Ⅱ);8,11,13,15-四烯松香烷-18-烷酸(8,11,13,15-abietatraen-18-oic acid,Ⅲ);6α-羟基尼刀瑞尔醇(6α-hydroxy nidorellol,Ⅳ);2个黄酮类化合物5-羟基-3,4′,7-三甲氧基黄酮(5-hydroxy-3,4′,7-trimethoxyflavone,V);3,5-二甲基莰非醇(3,5-dimethylkaempherol,Ⅵ);其余的分别为:熊果酸(ursolic acid,Ⅶ),肌醇(myoinositol,Ⅷ),β-谷甾醇(β-sitosterol,Ⅸ),β-香树素(β-amyrin,X).结论化合物Ⅰ～Ⅵ为首次从该种植物中分离得到,且化合物Ⅰ～Ⅳ分别为4种不同类型的二萜.熊果酸的含量高达1%,本植物可作为其资源植物.
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