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Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4
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- Author:
- No author available
- Journal Title:
- Acta Pharmaceutica Sinica
- Issue:
- 5
- DOI:
- No doi available
- Key Word:
- 桦褐孔菌;三萜;羊毛甾醇;桦褐孔菌醇;栓菌酸;抗氧化作用;氧化应激
Abstract： 桦褐孔菌(Inonotus obliquus)系多孔菌科药用真菌,主要分布于北纬45°～50°地区,在我国的黑龙江、吉林两省资源较丰富.民间广泛用于治疗一些恶性肿瘤[1].已有大量现代药理学研究证明,桦褐孔菌具有抗肿瘤、抗炎、抗病毒、降血糖、降血脂及保肝等广泛的药理作用[2-7].桦褐孔菌中的主要化学成分是羊毛甾烷型四环三萜类化合物,其中含量较高的有羊毛甾醇、桦褐孔菌醇、栓菌酸等,他们同时也是桦褐孔菌的主要活性成分;尤其是桦褐孔菌醇具有较好的抗肿瘤作用及抗突变、抗炎等活性[8-12],是桦褐孔菌的标志性成分.
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