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Advances in the study of nitric oxide-donating drugs

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Author:
No author available
Journal Title:
ACTA PHARMACEUTICA SINICA
Issue:
11
DOI:
10.3321/j.issn:0513-4870.2009.11.003
Key Word:
一氧化氮;信使物质;效应分子;NO供体型药物;nitric oxide (NO);messenger;effector;NO-donating drugs

Abstract: Nitric oxide (NO) as a messenger and/or effector plays important roles in vivo. The decreased availability of NO or dysfunction in NO signaling has often been implicated in the development and progression of diseases, and design and research of NO-donating drugs has become one of the important strategies in drug discovery. In connection with authors' scientific practice, this article reviews the recent advances in the research of NO-donating drugs.

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