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Fucoidan: advances in the study of it's anti-inflammatory and anti-oxidative effects
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- Author:
- No author available
- Journal Title:
- ACTA PHARMACEUTICA SINICA
- Issue:
- 12
- DOI:
- 10.3321/j.issn:0513-4870.2008.12.004
- Key Word:
- 褐藻多糖硫酸酯;抗炎活性;抗氧化活性
Abstract： 褐藻多糖硫酸酯是一种天然来源的海藻多糖,具有多种生物活性,尤其是抗炎和抗氧化应激活性近年来受到了研究者的广泛关注.研究表明,褐藻多糖硫酸酯可通过与细胞膜上的选择素结合而参与炎症的病理过程,也可作为清道夫受体的配体发挥抗炎症作用,它亦参与调节多种炎症相关因子的生成.褐藻多糖硫酸酯还可以抑制活性氧自由基的生成并促进其清除,从而表现出抗氧化活性.
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