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Progress on the studies of cyclic lipopeptides

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Author:: No author available

Journal Title:: ACTA PHARMACEUTICA SINICA

Issue:: 9

DOI:: 10.3321/j.issn:0513-4870.2008.09.001

Key Word:: 微生物;环脂肽;化学成分;生物活性;结构鉴定

Abstract：环脂肽又名脂酰肽,是一类结构新颖的环状肽类化合物,具有抗菌、抗肿瘤、抗炎等广泛的生物活性,近年来受到人们的广泛关注.环脂肽类成分主要来源于微生物的次生代谢产物,包括蓝细菌(Cyanobacterium)、细菌(Bacterium)及放线菌等微生物,其中海洋细菌主要包括芽胞杆菌属(Bacillus)和假单胞菌属(Pseudomonas).本文拟就近年来环脂肽类成分研究进展进行综述.

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