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Recent advances in the study of dendrimers-based drug delivery systems

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Author:: No author available

Journal Title:: ACTA PHARMACEUTICA SINICA

Issue:: 9

DOI:: 10.3321/j.issn:0513-4870.2007.09.003

Key Word:: 树状大分子;药物载体;基因载体

Abstract：树状大分子是一类高度枝化的单分散性大分子,其内部结构呈疏水性,外表面呈亲水性,可称为"单分子胶束".本文在简介树状大分子的发展及结构特点的基础上,阐述了树状大分子作为药物载体的作用特点及其与药物的结合方式.目前,树状大分子在介导药物靶向传递及基因转染等方面的应用也备受关注,是一种颇有发展潜力的新型载体.

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