Paper - WANFANG MED ONLINE

You Position: Home > Paper

Targeting of nitric oxide-donor and related drugs

( views:275, downloads:31 )

Author:: No author available

Journal Title:: ACTA PHARMACEUTICA SINICA

Issue:: 6

DOI:: 10.3321/j.issn:0513-4870.2006.06.001

Key Word:: 靶向作用;一氧化氮;一氧化氮供体;药物

Abstract： @@ 一氧化氮(NO)是一种自由基气体分子,早在1972年就由Joseph Priestley发现,但一直到20世纪80年代它在体内的生物学特性才得到确认[1].

Reference

[1]Kenneth V.Honn,Ming Xian,Mohit Trikha,etc.Synthesis of peptide-diazeniumdiolate conjugates: towards enzyme activated antitumor agents[J].2001,42(14).
[2]David A, Wink,James B, Mitchell.Nitric oxide and cancer: an introduction.[J].2003,34(8).
[3]S, Moncada,R M, Palmer,E A, Higgs.Nitric oxide: physiology, pathophysiology, and pharmacology.[J].1991,43.
[4]Paul J, Shami,Joseph E, Saavedra,Lai Y, Wang,etc.JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.[J].2003,2.
[5]J E, Saavedra,T R, Billiar,D L, Williams,etc.Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver.[J].1997,40.
[6]中国药科大学.齐墩果酸偶联衍生物及其药物用途[P].2004.
[7]Keefer LK.Nitric oxide (NO)- and nitroxyl (HNO)-generating diazeniumdiolates (NONOates): emerging commercial opportunities.[J].2005,5(7).
[8]Wang J,Sharp L,Cantauria G,etc.Targeting nitric oxide to cancer cells: cytotoxicity studies of glyco-S-nitrosothiols.[J].1999,9(15).
[9]Gregory R J, Thatcher,Adrian C, Nicolescu,Brian M, Bennett,etc.Nitrates and NO release: contemporary aspects in biological and medicinal chemistry.[J].2004,37(8).
[10]Liu L,Xu W,Charles lG,etc.Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents.[J].2000,2(6).
[11]Y C, Hou,A, Janczuk,P G, Wang.Current trends in the development of nitric oxide donors.[J].1999,5.
[12]S, Moncada,A, Higgs,R, Furchgott.International Union of Pharmacology Nomenclature in Nitric Oxide Research.[J].1997,49.
[13]Iwakiri Y,Cadelina GW,Loureiro Silva MR,etc.A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats.[J].2003,39(6).
[14]Xiaoping Tang,Peng George Wang,Ming Xian,etc.Glycosylated diazeniumdiolates:a novel class of enzyme-activated nitric oxide donors[J].2001,42(23).
[15]Buzard GS,Findlay VJ,Saavedra JE,etc.Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug.[J].2004,65(5).
[16]A. Giuffre,G. Stubauer,M. T. Wilson,etc.Nitric oxide and cellular respiration[J].1999,56(7).
[17]L J, Ignarro,G M, Buga,K S, Wood,etc.Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.[J].1987,84.
[18]Joseph A, Hrabie,Larry K, Keefer.Chemistry of the nitric oxide-releasing diazeniumdiolate ("nitrosohydroxylamine") functional group and its oxygen-substituted derivatives.[J].2002,102(4).
[19]Wu X,Xian M,Tang X,etc.Synthesis and cytotoxicities of mannose conjugated S-nitroso-N-acetylpenicillamine (SNAP).[J].2002,10(7).
[20]K, Xie,S, Huang,Z, Dong,etc.Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells.[J].1995,181.
[21]Bruno Giardina,Giuseppe E Martorana,Roberto Scatena,etc.Nitric oxide donor drugs:an update on pathophysiology and therapeutic potential[J].2005,14(7).
[22]Fiorucci S,Antonelli E,Tocchetti P,etc.Treatment of portal hypertension with NCX-1000, a liver-specific NO donor. A review of its current status.[J].2004,22(2).
[23]Yongchun Hou,Xuejun Wu,Wenhua Xie,etc.The synthesis and cytotoxicity of fructose-1-SNAP,a novel fructose conjugated S-nitroso nitric oxide donor[J].2001,42(5).
[24]S H, Juang,K, Xie,L, Xu,etc.Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the murine inducible nitric oxide synthase gene.[J].1998,9.