EFFECT OF HOWIINOL(GHM-10) ON THE STRUCTURE OF DNA MOLECULES AND ACTIVITY OF DNA TOPOISOMERASE II IN L1210 CELLS

( views:, downloads: )
Author:
He Jianhua()
Xu Chengxiong()
Journal Title:
ACTA PHARMACEUTICA SINICA
Issue:
Volume 34, Issue 01, 1999
DOI:
Key Word:

Abstract:

  • [1]何剑华,叶玉梅,徐承熊. 从海南哥纳香中分离的一种新化合物海南哥纳香醇甲的抗肿瘤作用. 药学学报,1998,33:493
  • [2]何剑华,叶玉梅,徐承熊. 海南哥纳香醇甲(GHM-10)对体外L1210细胞的抗肿瘤活性. 药学学报,1998,33:566
  • [3]何剑华,徐承熊. 海南哥纳香醇甲GHM-10对L1210细胞生物大分子合成抑制的研究. 药学学报,1998,33:886
  • [4]Singh NP,McCoy MT,Tice PR,et al. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res,1988,175:184
  • [5]Wang LG,Zeng H. DNA-protein,DNA interstrand cross-links induced by camphoramine chloroacetic platinum in vitro. Acta Pharmacol Sin,1989,10:261
  • [6]Wang LG,Liu XM,Ji XJ. Determination of DNA topoisomerase II activity from L1210 cells-a target for screening antitumor agents. Acta Pharmacol Sin,1991,12:108
  • [7]Gedik CM,Ewen SWB,Collins AR. Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells. Int J Radiat Biol,1992,62:313
  • [8]刘晓梅,王龙贵. DNA拓扑异构酶与抗癌药研究. 国外医学药学分册,1989,16:129
  • [9]王龙贵,刘晓梅,籍秀娟. 以DNA拓扑异构酶II为靶点的一种抗癌药筛选的新方法. 癌症,1991,10:220
  • [10]Jaxel C,Taudou G,Portemer C,et al. Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanvalin A stimulated splenocytes. Biochemistry,1988,27:95
  • [11]Drake FH,Hofmann GA,Mong SM,et al. In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone. Cancer Res,1989,49:2578
  • [12]Jensen PB,Sorensen BS,Demant EJF,et al. Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4′-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage. Cancer Res,1990,50:3311
  • [13]Boritzki TL,Wolfard TS,Besserer JA. et al. Inhibition of type II topoisomerase by fostriecin. Biochem Pharmacol,1988,37:4063
  • [14]Tanabe K,Ikegami Y,Ishida R,et al. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. Cancer Res,1991,51:4903
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn