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DETERMINATION OF DIGOXIN-LIKE IMMUNOREACTIVE SUBSTANCES IN SERA OF 15 ELDER PATIENTS WITH CARDIAC INSUFFICIENCY
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- Author:
- No author available
- Journal Title:
- ACTA PHARMACEUTICA SINICA
- Issue:
- 9
- DOI:
- 10.3321/j.issn:0513-4870.1998.09.004
- Key Word:
- 地高辛样免疫活性物质;荧光极化免疫分析法;地高辛;心功能不全
Abstract： 采用荧光极化免疫分析法,检测了15例老年心功能不全病人血清地高辛样免疫活性物质(DLIS)浓度.以TDx仪最低检测限0.256 nmol·L-1为阳性检测标准,DLIS检出阳性率为46.7%(7/15),浓度范围0.26～1.52 nmol·L-1,平均浓度0.55±0.44 nmol·L-1;其中1例病人血清DLIS浓度高达1.52 nmol·L-1.结果表明老年心功能不全患者血清中含有较高水平的DLIS;提示对这些患者若因病情需要而用地高辛治疗时,其后的血浓度测定结果易引起"过高估计",应当谨慎地评价地高辛血浓度测定结果.
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