Normal apparent diffusion coefficient values of different regions of pancreas

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Author:
PAN Chun-shu(Department of Radiology,Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
MA Chao(Department of Radiology,Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
WANG Jian(Department of Radiology,Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
WANG He()
CHEN Shi-yue(Department of Radiology,Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
ZHANG Hua-gao()
LU Jian-ping(Department of Radiology,Changhai Hospital, Second Military Medical University, Shanghai 200433, China)
Journal Title:
Chinese Journal of Pancreatology
Issue:
Volume 12, Issue 05, 2012
DOI:
10.3760/cma.j.issn.1674-1935.2012.05.006
Key Word:
Pancreas; Diffusion magnetic resonance imaging; Apparent diffusion coefficient

Abstract: Objective To investigate and determine the apparent diffusion coefficient (ADC) values in different anatomical regions of normal pancreas.Methods A total of 383 volunteers with normal pancreas were included in this study.Single-shot echo planar imaging diffusion weighted imaging (SSEP-DWI; b value =0,500 s/mm2) was employed to determine the ADCs in the head,neck,body and tail parts of the pancreas.Statistical analysis was performed by using Kruskal-Wallis and Wilcoxon signed rank tests.Results The ADCs in the head,neck,body and tail parts of the pancreas was (1.52 ± 0.29) × 10-3,( 1.64 ± 0.34) ×10-3,(1.67±0.35) × 10-3,(1.58 ±0.31) × 10-3 mm2/s,the Kruskal-Wallis test results showed a significant difference of mean ADCs among the different anatomical regions (chi square =44.8748,P <0.0001 ).Wilcoxon signed rank test results showed the mean ADCs differed remarkably between the head and neck ( P < 0.0001 ),head and body ( P < 0.0001 ),head and tail ( P =0.0008 ),neck and tail (P =0.0062 ),body and tail (P <0.0001),respectively.The mean ADCs between the neck and body was not significantly different (P =0.1181 ).Conclusions The mean ADC values of normal pancreas vary significantly within different anatomical regions,which can serve as a guide for DW1 and ADC in clinical application and research of pancreatic diseases.

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