Kansui root therapy for severe acute pancreatitis with high intra-abdominal pressure

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Author:
HE Jun-ming(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
CAI Shi-xia(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
ZHONG Xiao-sheng(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
QIU Cheng-jiang(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
HUANG You-xing(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
WANG Song(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
LIU Xian-feng(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
TAN Zhi-jian(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
CAI Bing-qin(Department of Hepatobiliopancreatic Surgery,Guangdong Province Hospital of Traditional Chinese Medicine,Guangzhou 510120,China)
Journal Title:
CHINESE JOURNAL OF PANCREATOLOGY
Issue:
Volume 10, Issue 06, 2010
DOI:
10.3760/cma.j.issn.1674-1935.2010.06.004
Key Word:
Pancreatitis,acute necrotizing;Euphorbia kansui;Pressure;Jiexiong syndrome

Abstract: Objective To investigate the treatment effects of Kansui root on severe acute pancreatitis (SAP) with abdominal compartment syndrome (ACS).Methods 16 cases of SAP were randomly divided into kansui root treatment group and control group according to random number table.Patients in control group received routine treatment including fasting, anti-shock, antibiotics and nutritional support.And the patients in kansui root group received routine treatment plus kansui root therapy.The clinical and laboratory parameters were determined and compared between the two groups.Results The relieving time of abdominal pain, bowel sound, the recovery time of hyperamylasemia, body temperature and leukocyte count in treatment group was (7.6±2.3)d, (6.1 ±3.1)d, (5.9±3.3)d, (5.2 ±3.2) d, (6.3 ±2.1)d, which were significantly shorter than those in control group [ ( 11.7 ± 2.1 ) d, ( 11.2 ± 2.3d, ( 10.2 ± 2.7) d, (9.2 ± 3.5 ) d, ( 11.1 ±3.3)d, P<0.01 ) ].At the 3rd, 4th and 5th day, the intra-abdominal pressure in treatment group were also significantly lower than those in control group[ ( 19.8 ±3.1 )cmH2O vs(23.7 ±2.9) cmH2O, ( 12.3 ±2.7) cmH2O vs (21.3±1.5)cmH2O,(8.2±3.1)cmH2O vs (17.3 ±2.3)cmH2O,P<0.05].Conclusions Severe acute pancreatitis has close relationship with Jiexiong syndrome in traditional chinese medicine.Kansui root is an effective therapy for alleviating high intra-abdominal pressure.

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