Cost-utility analysis of surgical treatment for SAP

( views:, downloads: )
LUO Dan(Department of Hepatobiliary Surgery,Peple's Hospital of Guizhou Province,Guiyang 553002,China)
LEI Ruo-qing()
XU Zhi-wei()
HAN Tian-quan()
TANG Yao-qing()
ZHANG Sheng-dao()
Journal Title:
Volume 9, Issue 05, 2009
Key Word:
Pancreatitis; acute necrotizing; Quality-adjusted life years; Cost-benefit analysis

Abstract: Objective To assess the cost-utility and medical economics of surgjcal treatment for SAP.Methods A retrospective study of SAP patients admitted from January to December 2003 to Ruijin Hospital was carried out.The cost of treatment was obtained from financial department and patients questionnaire;health-related quality of life was assessed by using the SF-36 brief questionnaire and the results were compared with normal population and were converted into rQALY,then utility scores were obtained so as to conduct CUA (cost-utility analysis)and related factors were analyzed.Results 98 patients with SAP were discharged,85 were discharged healthy;of them,59 patients had complete records were followed up,2 died during follow up,with a mortality of 3.4%,one patients could not finish the questionnaire and 6 did not respond,finally 50 finished the questionnaire;the total cost in hospital was 9899095 yuan,per capita 101011 yuan;the corrected post-discharge cost was 681737 yuan;the total cost was 10580832 yuan.The cost of medication was the highest,which accounted for 56%of all the cost.The means and deviations for each of eight scales(PF,RP,RE,BP,VT,MH,SF,GH)scores of SF-36 in SAP patients were 83.00±14.64,61.5.0±42.32,68.67±36.52,79.98±14.90,68.80±18.94,72.40±14.75,75.00±17.53,64.70±18.28.compared with normal population,gained 1929.05 QALYs;the cost-utility analysis was 5485 yuan per QALY.The patient's age,length of stay,chronic co-morbidity was associated with the cost of treatment.Conclusions SAP treatment in surgery department was justified in medical economics.Medication contributed to the most part of total costs.The related factors of cost included age,length of stay and chronic co-morbidity.

  • [1]中华医学会外科学分会胰腺外科学组.重症急性胰腺炎诊治原则草案.中华外科杂志,2001,39:963-964.
  • [2]Ware J,Gandek B.Overview of SF-36 health survey and the international quality of life assessment(IQOLA)project.J Clin Epidemiol,1998,51:903-912.
  • [3]方积乾.生存质量测定方法及应用.北京:北京医科大学出版社,2000:263-267.
  • [4]李宁秀,朝杰,李俊,等.四川省城乡居民SF-36评价参考值,华西医科大学学报,2001,32:43-47.
  • [5]刘朝杰,李俊,李宁秀,等.用SF-36评价健康状态效用,华西医科大学学报,2001,32:396-398.
  • [6]严俊,汪宏,李天霖.成本-效用分析原则及步骤.中国慢性病预防与控制,1994,2:171-173.
  • [7]Shaheen NJ,Hansen RA,Morgan DR,et al.the burdenof gastrointestinal and liver disease.Am J Gastroenterol,2006,101:2128-38.
  • [8]Soran A,Chelluri L,Lee KK,et al.Outcome and quality of life of patients with acute pancreatitis requiring intensive care.J Surg Res,2000,91:89-94.
  • [9]张文俊,李兆申,许国铭,等.早期空肠营养在重症急性胰腺炎治疗中的应用.胰腺病学,2002,2:208-210.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615