The value of DWI in diagnosis and differential diagnosis of pancreatic carcinoma from chronic lump type pancreatitis

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Author:
LU Jing(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
LU Jian-ping(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
WANG Fei(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
WANG Li(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
LIU Qi(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
HE Xin-hong(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
WANG Jian(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
WANG Bei(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
WU Yi-na(Department of Radiology, Changhai Hospital, Second Military Medical University,Shanghai 200433, China)
Journal Title:
CHINESE JOURNAL OF PANCREATOLOGY
Issue:
Volume 8, Issue 03, 2008
DOI:
Key Word:
Pancreatic disease;Diffusion magnetic resonance imaging;b value;Apparent diffusion coefficient

Abstract: Objective To evaluate the ability of diffusion-weighted imaging (DWI)in differentiating pancreatic carcinoma from chronic lump type pancreatitis. Methods Totally 38 cases of pancreatic cancer, 9 cases of chronic lump type pancreatitis, 15 cases of normal patients underwent DWI. DWI with b value=0, 500, 1 000 s/mm2 was performed twice. Apparent diffusion coefficient (ADC) was measured by analysis of imagines of ADC. Results The mean ADC value of 38 subjects with pancreatic carcinoma was (1.411± 0.101)×10-3 mm2/sec, the mean ADC value of 9 subjects with lump type pancreatitis was (1.053±0.113) ×10-3 mm2/sec, and the mean ADC value of normal pancreas subjects was (1.245±0.112)×10-3 mm2/s. The difference between the three groups were statistically significant (P<0.05). Conclusions DWI may have the clinical potential to differentiate chronic lump type pancreatitis from pancreatic carcinoma.

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