Comparative study of the inhibitory effect of angiogenesis inhibitor, TNP-470 and Gemcitabine on the growth and metastasis of pancreatic carcinoma

( views:, downloads: )
Journal Title:
Volume 3, Issue 03, 2003
Key Word:


  • [1]贾林,袁世珍.肿瘤抗血管治疗现状与血管生成抑制-细胞毒疗法.广州医学院学报,2000,28:82-84.
  • [2]Barinaga M. Designing therapies that target tumor bloodvessels. Science, 1997, 275:482 484.
  • [3]Konno H. Antitumor effect of the angiogenesis inhibitor TNP 470 on human digestive organ malignancy. Cancer ChemotherPharmacol, 1999,43:S85 89.
  • [4]贾林,袁世珍,黄文革,等.人胰腺癌裸小鼠胰腺内原位移植模型的建立.广州医药,2001,32:1 2.
  • [5]Furukawa T, Kubota T, Watanabe M, et al. A novel "petient like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. Cancer Res, 1993, 53:3070 3072.
  • [6]Rowe PM. Starve the tumor, save the patient. Lancet, 1997,349:108.
  • [7]Gervaz P, Fontolliet C. Therapeutic potential of the anti angiogenesis drugs TNP-470. Int J Exp Path, 1998, 79: 359362.
  • [8]Konno H, Tanaka T, Matsuda I, et al. Comparison of theinhibitlry effect of the angiogenesis inhibitor, TNP 470, and mitomycin C on the growth and liver metastasis of human colon cancer. Int J Cancer, 1995, 61:268-271.
  • [9]Burris HA Ⅲ , Moore M J, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreatic cancer: a randomized trial.J Clin Oncol, 1997, 15:2403-2413.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615