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Glucagonoma syndrome: Review of the Chinese literature
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PANCREATOLOGY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-1935.2002.04.002
- Key Word:
- 胰高血糖素瘤;胰腺;诊断;治疗
Abstract： 目的提高对GCGN的认识,改善其诊治水平.方法总结国内文献GCGN 25例及本院4例的诊治资料.结果 86.2%(25/29)患者有典型的GCGN特征,但几乎所有患者在病程的不同阶段曾被误诊.其中行胰体尾切除18例,Whipple手术及胆肠吻合各1例,肿瘤局部切除或摘除术2例,7例不适宜手术或拒绝手术治疗.病理结果示24例恶性,3例良性,2例性质不确定.治疗后多数患者短期内皮疹消退,症状改善,随访生存期超过2年以上的患者有5例.结论 GCGN临床少见,尤其缺乏特征性临床表现者极易误诊.影像学检查及GC测定有助于诊断.根治性或姑息性切除辅以化疗等措施为有效的治疗手段.
- [1]J A, Norton.Neuroendocrine tumors of the pancreas and duodenum.[J].1994,31(2).
- [2]陆汉明,朱熊,姜靖寰,等.胰高糖素瘤综合症[J].1981,(1).
- [3]Henry J G,Xue N,Kinder B K,etc.A 73-year-old man with hyperglycemia, skin rashes, anemia and weight loss.[J].1996.
- [4]E, Mozell,P, Stenzel,E A, Woltering,etc.Functional endocrine tumors of the pancreas: clinical presentation, diagnosis, and treatment.[J].1990,27(6).
- [5]赵玉沛,王振捷,蔡力行,等.胰高血糖素瘤综合征[J].1994,(6).
- [6]秦士杰,许伦尧,白钢,等.恶性胰岛A细胞瘤一例报告[J].1982,(4).
- [7]Wermers RA,Fatourechi V,Kvols LK.Clinical spectrum of hyperglucagonemia associated with malignant neuroendocrine tumors.[J].1996,71(11).
- [8]C N, Mallinson,S R, Bloom,A P, Warin,etc.A glucagonoma syndrome.[J].1974,2.
- [9]征革凡,杨文英,许丽.胰高血糖素瘤综合征1例[J].1996,(3).