Relationship between p21ras and angiogenesis in chronic pancreatitis,pancreatic cancer and its clinical significance

( views:, downloads: )
Journal Title:
Volume 1, Issue 01, 2001
Key Word:


  • [1]Lowenfels AB, Maisonneuve P, Cavallini G, et al. Pancreatitis and the risk of pancreatic cancer. N Engl J Med, 1993,328(20):1433-1437
  • [2]Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorgenesis. Cell, 1996, 86 ( 3 ):353-364
  • [3]Caldas C,Hahn SA,Hruban RH,et al. Detection of K-ras muta-tions in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. Cancer Res, 1994, 54 (3): 3568-3573
  • [4]Uehara H, Nakaizumi A, Baba M, et al. Diagnosis of pancreatic cancer by K-ras point mutation and cytology of pancreatic juice.Am J Gastroenterol, 1996,91(8): 1616-1621
  • [5]Horak ER, Leek R, Klenk N, et al. Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indica-tor of node metastases and survival in breast cancer. Lancet,1992, 340(8828): 1120-1124
  • [6]Rak J, Mitsuhashi Y, Bayko L , et al. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res, 1995,55(20):4575-4580
  • [7]Folkman J,Watson K, Ingber D, et al. Induction of angiogene-sis during the transition from hyperplasia to neoplasia. Nature,1989,339(6219):58-61
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615