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Mechanism and significance of immunological changes in sepsis
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- Author:
- No author available
- Journal Title:
- Chinese Pediatric Emergency Medicine
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1673-4912.2012.05.005
- Key Word:
- 脓毒症;Toll样受体;中性粒细胞;树突状细胞;调节性T细胞;Th1/Th2;Sepsis;Toll-like receptors;Neutrophils;Dendritic cells;Regulatory T cells;Th1/Th2
Abstract： Sepsis is thought to be systemic inflammatory response syndrome that is activated by invasive infection and characterized by the involvement of inflammation,infection,immunological reaction,coagulation and tissue damage.The imbalance between the pro-and anti-inflammatory response mediated by immunologic disorder plays an important part in the progress of sepsis.Therefore,the immunological mechanisms and changes of Toll-like receptors,neutrophils,dendritic cells and regulatory T cells in sepsis are briefly focused on in the article.
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