Abstract： Objective To evaluate the accuracy of prediction for consciousness using entropy index during recovery from propofol-remifentsnil general anesthesia as compared with brain bispoctral index (BIS).Methods Between October and December 2010, 50 patients undergoing selective gynecologic laparoscopic surgery under general anesthesia maintained with propofol-remifentanil by target-controlled infusion in our hospital were included in this study. The values of response entropy (RE), state entropy (SE), BIS, effectsite concentration of propofol (Ce), mean arterial pressure (MAP) and heart rate (HR) were monitored at different time points after operation, and the probabilities (Pk values) of throe prediction for conscionsness were calculated and compared. The EC05, EC95 values and 95％ CI for RE, SE and BIS at recovery of consciousness (ROC) were calculated, respectively. The correlations between RE, SE, BIS, Ce and changes in consciousness during recover were analyzed. Results There were significant correlations between RE, SE, BIS, Ce and consciousness during recovery from anesthesia (rs=0.898, 0.901, 0.899,and -0.935, all P＜0.01). The values of RE, SE and BIS at ROC were 89.5±2.8, 75.2±6.8, and 81.6±2.6,all with a Pk value higher than 0.5 and higher than those of MAP and HR (all P＜0.01 ). The EC05 values and 95％CI of RE, SE and BIS at ROC were 84.7(81.2,86.8), 58.3(52.5,61.1 ), and 61.2(48.2,68.2), and the EC95 values and 95％CI were 92.4(90.1,94.8), 72.2(67.5,78.2) and 84.3(78.6,92.8), respectively. Among 90％ of patients, the range of RE was smallest at ROC compared with the greatest range in BIS.Conclusions While both entropy index and BIS accurately predict consciousness during recovery from propofol-remifentanil general anesthesia, entropy index may be more effective than BIS in the prediction.