Relationship among related parameters of healthy human eye anterior segment structure detected by anterior segment optical coherence tomography

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Author:
ZENG Yang-fa(Zhongshan Ophthalmic Center, Sun Yat-sen University)
LIU Xing(Zhongshan Ophthalmic Center, Sun Yat-sen University)
WANG Tao()
ZHONG Yi-min(Zhongshan Ophthalmic Center, Sun Yat-sen University)
LI Mei(Zhongshan Ophthalmic Center, Sun Yat-sen University)
HE Ming-guang(Zhongshan Ophthalmic Center, Sun Yat-sen University)
Journal Title:
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
Issue:
Volume 15, Issue 05, 2009
DOI:
10.3760/cma.j.issn.1674-1927.2009.05.003
Key Word:
Tomography;optical coherence;Glaucoma;angle-closure;Anterior chamber;Lens thickness;Lens positions

Abstract: Objective To analyze the relationship among parameters of healthy human eye anterior segment structure detected by anterior segment optical coherence tomography (AS-OCT), and to explore the effect of age on these parameters. Methods AS-OCT was performed in 211 healthy people (211 eyes) to measure the parameters of anterior segment structure, including anterior chamber depth (ACD), anterior chamber horizontal diameter (ACHD), anatomy anterior chamber depth (AACD), lens thickness (LT), ciliary band length (CBL) , lens position (LP) and iris thickness (IT). These parameters were compared between men and women. Relationship among the parameters was analyzed, and effect of age on anterior segment structure biometric values was evaluated. Results The values of ACD, ACHD, AACD, CBL, IT and LP were significantly higher in male than those in female[ACD: (2.87±0.38) mm vs (2.66±0.40) mm; ACHD: (11.73±0.43) mm vs (11.53±0.36) mm;AACD: (3.09±0.19) mm vs (3.00±0.19) mm;CBL: (0.20± 0.09) mm vs (0.17±0.09) mm;iT: (0.36±0.08) mm vs (0.34±0.08) mm; LP: (5.11±0.26) mm vs (4.91± 0.28) ram; all P<0.05]. The value of LT was not significantly different between men and women (P=0.955). Age had no significant effect on AACD, IT, LP and CBL (all P>0.05). ACHD was negatively correlated with age (r=-0.148, P=0.032). LT was positively correlated with age (r=0.646, P=0.000). LT was negatively correlated with ACD (r=-0.714, P=0.000). LT had no significant effect on LP using regression analysis. Conclusions The anterior segments biometric structure of female is narrower than that of male. With aging, the narrowing of ACD is resulted from LT increment. And LP of healthy eyes does not change with aging and LT increment.

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