The Relationship between Matrix Metalloproteinases and Metastasis of Lung Cancer

( views:, downloads: )
Tian Dong-bo()
YANG Yu-hao()
Journal Title:
Volume 11, Issue 03, 2005
Key Word:


  • [1]Konttinen YT,Ainola M,Valleala H,et al. Analysis of 16 different matrix metalloproteinases(MMP1 to MMP 20)in the synovial membrane:different profiles in trauma and rheumatoid arthritis[J].Ann Rheum Dis,1999,58(11):691.
  • [2]Ozenci V,Rinaldi L,Teleshova N,et al. Metalloproteinases and their tissue inhibitor in multiple sclerosis[J].Jautoimmun,1999,12(4):297.
  • [3]Farias E,Ranuncolo S,Cresta C,et al. Plasma metalloproteinases activity is enhanced in the eugbulin fraction of breast and lung cancer patient[J].Int J Cancer,2000,89(4):389.
  • [4]Johnson N,Ahonen M,kahari VM,et al. Matrix metalloproteinases in tumor invasion[J].CMLS Cell Mol Life Sci,2000,57(1):5.
  • [5]Gomez DE,Alonso DF,Yoshiji H,et al. Tissue inhibitor of metalloproteinases structure,regulation and biological functions[J].Eur J Cell Biol,1997,74(1):111.
  • [6]Stephanie C,Graeme I. Matrix metalloproteinase expression in tumor invasion and metastasis[J].J Pathol,1999,189(3):300.
  • [7]Galateau-Salle FB,Luna RE,Horiba K,et al. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in bronchial squamous preinvasive lesions[J].Hum Pathol,2000,31(3):296.
  • [8]Thomas P,Khokha R,Shepherd FA,et al. Differential expression of matrix metalloproteinases and their inhibitors in non-small cell lung cancer[J].J Pathol,2000,190(2):150.
  • [9]Suzuki M,Iizasa T,Fujisawa T,et al. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in non-small-cell lung cancer[J].Invasion & metastasis,1998,18(3):134.
  • [10]Fujise N,Nanashim A,Taniguchi Y,et al. Prognostic impact of cathepsin B and matrix metalloproteinases-9 in pulmonary adenocarcinomas by immunohistochemical study[J].Lung Cancer,2000,27(1):19.
  • [11]Michael M,Babic B,Khokha R,et al. Expression and prognostic significance of metalloproteinases and their tissue inhibitors in patients with small lung cancer[J].J Clin Oncol,1999,17(6):1802.
  • [12]Nawrocki B,Polette M,Marchand V,et al. Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas:Quantificative and morphological analyses[J].Int J Cancer,1997,72(4):556.
  • [13]Delebecq TJ,Porte H,Zerimech F,et al. Overexpression level of stromelysin 3 is related to the lymph node involvement in non-small cell lung cancer[J].Clin Cancer Res,2000,6(3):1086.
  • [14]Gringon DJ,Sakr W,Ravery V,et al. High level of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression associated with poor outcome in invasive bladder cancer[J]. Cancer Res,1996,56:1654.
  • [15]Herbst RS,Yano S,Kuniyasu H,et al. Differential expression of E-cadherin and type IV collagense genes predicts outcome in patients with stage I non-small cell lung carcinoma[J].Clin Cancer Res,2000,6(3):790.
  • [16]Bolon I,Devouassoux M,Robbert C,et al. Expession of urokinase-type plasmiregen activator,stromel-ysin 1,stromelysin 3,and smatrilysin genes in lung carcinomas[J]. Am J Pathol,1997,150,1619.
  • [17]Caneta-Soler R,Lizky L,Lubensky T,et al. Localization of the 92kD gelatinase mRNA in squamous cell and adeno carcinomas of the lung using in situ hybridization[J].Am J Pathol,1994,164:518.
  • [18]Soini Y,Paakko P,Autio-Harmainen H,et al .Genes of laminin B1 chain,al(IV)chain of type IV collagen and 72kD type IV collgenase are mainly expressed by the stromal cells oflung carcinomas[J]. Am J Pathol,1993,142:1622.
  • [19]Zucker S,Lysik RM,Malik M,et al.Secretion of gelateinases and tissue inhibitors of metalloproteinase by human lung cancer lines and revertant cell lines :not an invariant correlation with metastasis[J].Int J Cancer,1992,52(3):366.
  • [20]Ylisirnio S,Hoyhtya M,Turpeenniemi HT,et al. Serum MMP-2,-9 and TIMP-1,-2 in lung cancer-TIMP-1 as a prognostic maker[J].Anticancer Res,2000,20(2b):1311.
  • [21]Lizasa T,Fujisawa T,Suzuki M,et al.Elevated levels of circulating plasma matrix metalloproteinases 9 in non-small cell lung cancer patients[J].Clin Cancer Res,1999,5(1):149.
  • [22]Togawa D,Koshino T,Saito T,et al. Highly activated matrix metalloproteinase-2 secreted from clones of mstastatic lung nodules of nude mice injected with human fibrosarcoma HT1080[J].Cancer Lett,1999,146(1):25.
  • [23]Itoh T, Tanioka M,Tyoshida H,et al. Reduced angiogenesis and tumor progression in gelatinase A-dificient mice[J].Cancer Res,1998,58(5):1048.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615