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Effect of APBMV on Immunological Function of the Mice with X-ray
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- Author:
- No author available
- Journal Title:
- JOURNAL OF MODERN CLINICAL MEDICAL BIOENGINEERING
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1008-634X.2004.04.004
- Key Word:
- 蝎毒;多肽;免疫功能;辐射
Abstract： 目的研究蝎毒抗癌多肽(APBMV)对X射线照射小鼠免疫功能的影响.方法小鼠60只,随机均分为正常对照组、照射对照组、照射中药组共3组,照射中药组采取腹腔灌注APBMV结合X线照射.观察各组白细胞计数、脾脏指数、胸腺指数及免疫荧光染色法和流式细胞仪测定外周血T淋巴细胞亚群等指标.结果照射对照组的白细胞计数、脾脏指数、胸腺指数、CD4、CD8亚群与其它两组比较均明显下降(p<0.01),而照射中药组虽有下降,但与正常对照组对比无显著性差异.结论 APBMV对X射线照射小鼠免疫功能有一定改善及保护作用.
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