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Individual Allergens as Risk Factors for Asthma and Bronchial Hyperresponsiveness in Guangzhou Schoolchildren
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- Author:
- No author available
- Journal Title:
- JOURNAL OF MODERN CLINICAL MEDICAL BIOENGINEERING
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1674-1927.2003.03.006
- Key Word:
- 过敏原;哮喘;特应性;气道高反应性;儿童
Abstract： 目的探讨广州在校儿童中个人过敏原与哮喘症状及气道高反应性(BHR)间的关系, 明确个人过敏原在儿童哮喘进展中的作用.方法采用整群抽样的方法,对广州市10岁在校学龄儿童应用ISAAC(the International Study of Asthma and Allergies of Childhood)第二阶段研究方案进行研究,内容包括家长书面问卷(n=3565),皮肤过敏原点刺试验(n=1094)及乙酰甲胆碱支气管激发试验(n=177).结果问卷调查近期喘息率为3.4%,特应性阳性率为30.8%,过敏原阳性率以尘螨最高,其次为蟑螂,第三为猫毛.多因素 logistic回归分析显示,特应性(即≥1种过敏原阳性)不是儿童近期喘息及(BHR)独立的危险因素,屋尘螨、粉尘螨与近期喘息及(BHR)显著相关,猫毛与近期喘息也有显著的关联性,蟑螂过敏与近期喘息及(BHR)均无关.结论广州市儿童特应性并非哮喘症状及BHR独立的危险因素,尘螨仍是当前广州市儿童哮喘的主要病因之一.
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