Study on Antioxidation of Succinic Di-(3β-hydroxyandrost-5-en-17-one) Ester

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Journal Title:
Journal of Modern Clinical Medical Bioengineering
Volume 7, Issue 01, 2001
Key Word:

Abstract: Objective To study antioxidation ofDi-(3β-hydroxyandrost-5-en-17-one) ester (AST), a new compound which was structure derivated from active substance from Asterias amurensis. Methods Samples of tissues homogenates were pretreated with AST, then, addition of FeSO4+Cysteine(Cys) or not, the generation of malondialdehyde(MDA) was examined. Results The production of lipid peroxides in normal cardiac, liver homogenate of rat and rabbit,elevation of production of lipid peroxides induced by and FeSO4+Cys in. homogenate Conclusions AST have the effect of antilipid peroxidation on rats and rabbits' cardiac and liver tissue.

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