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Analgesic effect and security of tramadol/acetaminophen during perioperative total knee arthroplasty
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- Author:
- No author available
- Issue:
- 26
- DOI:
- 10.3969/j.issn.1673-8225.2012.26.007
- Key Word:
- 多模式镇痛;全膝关节置换术;氨酚曲马多;静脉自控镇痛;疼痛;人工关节
Abstract： 背景:镇痛治疗在人工全膝关节置换的恢复过程中发挥着重要作用,是进行有效功能锻炼、提高围术期生活质量的保证.目的:评价人工全膝关节置换围术期联合应用氨酚曲马多和静脉自控镇痛的有效性和安全性.方法:选取2010-09/2011-09在山东大学附属省立医院行单侧人工全膝关节置换的患者70例,多模式镇痛组使用静脉自控镇痛的同时口服氨酚曲马多至置换后第7天;对照组仅使用静脉自控镇痛.结果与结论:多模式镇痛组置换后的前3 d目测类比评分均低于对照组(P＜0.05),功能锻炼开始后两组评分差异无显著性意义,多模式镇痛组置换后第7天膝关节活动度和治疗总体满意度高于对照组(P＜0.05),不良反应的发生率和严重程度方面两组之间差异无显著性意义.结果可见人工全膝关节置换围术期应用氨酚曲马多结合静脉自控镇痛能提高功能锻炼的质量和治疗满意度,且未增加药物不良反应的风险.
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