Abstract： Objective To study the effect of different gastrointestinal decompression methods on patients' recovery of gastrointestinal function after colon cancer operation.Methods 64 patients with colon cancer were randomly divided into observation group (33 cases) and control group (31 cases).The observation group received no vacuum suction after the surgery,while the control group received negative pressure suction to drainage gastric fluid.Two groups' gastric fluid drainage volume,postoperative discomfort,the incidence rate of complications,and the recovery of gastrointestinal function were compared.Results The gastric fluid drainage volumes on the day of surgery and the first day after surgery in the observation group were (52.73 ± 12.06)ml and (123.03 ± 12.87) ml,while those in the control group were (122.58 ± 12.90) ml and (276.13 ± 14.71) ml,and the differences were statistically significant (t =-22.33,-44.25,respectively; P ＜ 0.05).The postoperative discomfort,the incidence rate of complications and gastric fluid drainage volumes on the 2nd and 3rd day after surgery in two groups were not significantly different (P ＞ 0.05).The time of anus exsufflation,gastric tube removal and regular diet recovery in the observation group was (2.87 ± 0.73),(3.48 ± 0.51),(8.64±0.60)d,while that in the control group was (3.87 ±0.81),(4.19 ±0.54),(9.61 ±0.67)d,and the differences were statistically significant (t =-5.49,-5.40,-6.15,respectively; P ＜ 0.05).Conclusions No vacuum suction after colon cancer surgery can promote patients' recovery of gastrointestinal function after colon cancer operation including early removal of the gastric tube and regular diet,as well as reduce the workload of the nurse,thus is worthy of clinical application and popularization.