You Position: Home > Paper
Research Progress on Synthesis and Application of p-Menthane-3,8-diol
( views:307, downloads:0 )
- Author:
- No author available
- Journal Title:
- Natural Product Research and Development
- Issue:
- 8
- DOI:
- 10.3969/j.issn.1001-6880.2012.08.030
- Key Word:
- 对(艹孟)烷-3,8-二醇;合成方法;应用
Abstract： 对(艹孟)烷-3,8-二醇是一种具有生物活性的化合物,主要来源于柠檬桉精油,可直接用于香水、杀虫剂和药品等.通常采用化学和生物化学的方法合成对(艹孟)烷-3,8-二醇,以替代从柠檬桉叶油分离得到的天然产品.以香茅醛为原料通过Prins环缩合和水解,或者通过Solanum aviculare悬浮培养方式进行生物转化得到对(艹孟)烷-3,8-二醇；通过薄荷醇的氧化,或者以2-丁烯醛为原料与甲基锂、NaClO2等试剂经过较长步骤也可合成对(艹孟)烷-3,8-二醇.对(艹孟)烷-3,8-二醇可应用于制造驱虫剂、凉味剂、药物或者化妆品的添加剂以及海水防护涂料添加剂等.
- [1]Haruki Tsuruta,Yoko Yuasa,Yoshifumi Yuasa.A Practical and Efficient Synthesis of p-Menthane-3,8-diols[J].2000,4(3).
- [2]Shojiro Maki,Katsuhiro Konno,Hiroaki Takayama.Selective oxidation of terminal isopropyl groups to tertiary alcohols by electrochemical methodology[J].1997,38(40).
- [3]Valterova I,Novotny M,Vanek T,etc.Biotransformation of citronellal by Solanum aviculare suspension cultures: preparation of p-menthane-3,8-diols and determination of their absolute configurations.[J].2003,66(9).
- [4]Benjamin C. Clark Jr.,Theresa S. Chamblee,Guillermo A. Iacobucci.Acid-catalyzed cyclization of terpenoids in a micellar system. Selectivity and rate enhancement in the cyclization of citronellal[J].1984,49(23).
- [5]Yoshinori Asakawa,Reiko Matsuda,Motoo Tori,etc.Preparation of biologically active substances and animal and microbial metabolites from menthols, cineoles and kauranes[J].1988,27(12).
- [6]Barasa SS,Hassanali A,Lwande W,etc.Repellent activities of stereoisomers of p-menthane-3,8-diols against Anopheles gambiae (Diptera: Culicidae)[J].2002,39(5).
- [7]Howard E. Zimmerman,James English Jr..Stereoisomerism of Isopulegol Hydrates and Some Analogous 1,3-Diols[J].1953,75(10).
- [8]Atta ur Rahman,Asif F,Choudhary MI,etc.Fungal transformation of (1R,2S,5R)-(-)-menthol by Cephalosporium aphidicola[J].1998,61(11).