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α-Glucosidase Inhibitory and Antioxidant Activity of Magnolia Officinalis
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- Author:
- No author available
- Journal Title:
- Natural Product Research and Development
- Issue:
- 8
- DOI:
- 10.3969/j.issn.1001-6880.2012.08.024
- Key Word:
- 凹叶厚朴;α-葡萄糖苷酶抑制活性;抗氧化活性
Abstract： 首次采用96微孔板法检测贵州和河南产凹叶厚朴抑制α-葡萄糖苷酶活性；并采用DPPH、ABTS和FRAP三种方法测定其抗氧化活性.贵州产凹叶厚朴乙酸乙酯(IC50 =7.22 μg,/mL)和正丁醇提取部位(IC50=36.59 μg/mL),河南产凹叶厚朴石油醚(IC50=107.04 μg/mL)和乙酸乙酯提取部位(IC50=17.17μg/mL),它们的活性都远高于于阳性对照Acarhose( IC50=1081.27 μg/mL).贵州产凹叶厚朴乙酸乙酯提取部位清除ABTS自由基的能力最强(IC50=8.81 μg/mL),强于阳性对照BHT(IC50=11.94 μg/mL)；其次为河南产凹叶厚朴乙酸乙酯提取部位(IC50=12.73 μg/mL).研究结果表明,贵州产凹叶厚朴乙酸乙酯提取部位抑制α-葡萄糖苷酶和抗氧化活性最好.
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