Abstract: The essential oil of Elsholtzia densa Benth has been obtained by using water distillation and analyzed by GCMS.The content of the essential oil of E.densa was 0.12%.Retention indices and mass spectral data were used to identify 26 oil components,represented 76.04% of the total essential oil.In the antimicrobial and antiviral activities assay,the essential oil exhibited antimicrobial and antiviral activities.