Abstract: This paper studies the effect of time delays on a nonautonomous Lotka-Volterra predator-prey dispersal system which consists of n-patches, the prey species can disperse among n-patches, but the predator species is confined to one patch and cannot disperse. We study the delayed Lotka-Volterra system where the coefficients of dependent density terms are not always strictly positive. By using comparison theorem and delays functional differential equation basic theory, we show that the system is uni-formly persistent under some appropriate conditions in two cases. Our results suggest that under some conditions, the introduction and the variance of the time delays can be both harmless and profitless. Further, by using fixed point theorem, we obtain that there is at least a positive periodic solution under conditions for the permanence of sys-tem. These results are basically an extension and improvement of the known results for nonautonomous Lotka-Volterra systems.