Abstract： The kinetic model for multiple intravenous infusion is a piecewise continuous function. Steady-State characteristics of this model are studied for drugs obeying one-compartment open model. Relationships of blood concentration between single dosing and multiple dosing are derived in this paper, which shows the parameters of Steady-State kinetic model can be predicted by the parameters from single dosing model. Based on these studies, dosage regimens are discussed for clinical application.