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Recent progress in neurobiological mechanisms of depression

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Author:: No author available

Journal Title:: Acta Physiologica Sinica

Issue:: 4

DOI:: No doi available

Key Word:: 抑郁;神经递质;神经内分泌;神经免疫;神经营养因子;神经再生;表观遗传学

Abstract：阐明抑郁的神经生物学机制一直是神经科学领域的一个难题,不仅仅是由于抑郁症状的异质性及其病因的多样性,更因其某些症状无法在动物模型上模拟.尽管如此,近年来在抑郁发生机制及药物新靶点的研究上仍取得了一些重要进展.本文对目前抑郁发生机制的上流假说进行了概述和评价,并提出了一些未来可能的发展方向.

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