GRP75 overexpression inhibits apoptosis induced by glucose deprivation via Raf/Mek/Erk1/2 signaling pathway

( views:44, downloads:0 )
Author:
LI Hong-Yan()
YANG Ling()
LIU Wen()
ZUO Ji()
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 63, Issue 01, 2011
DOI:
Key Word:

Abstract:

  • [1]Kaul SC,Deocaris CC,Wadhwa R.Three faces of mortalin:A house keeper,guardian and killer.Exp Gerontol 2007;42(4):263-274.
  • [2]Pilzer D,Saar M,Koya K,Fishelson Z.Mortalin inhibitors sensitize K562 leukemia cells to complement-dependent cytotoxicity.Int J Cancer 2010; 126(6):1428-1435.
  • [3]Sadekova S,Lehnert S,Chow TY.Induction of PBP74/mortalin/Grp75,a member of the hsp70 family,by low doses of ionizing radiation:a possible role in induced radioresistance.Int J Radiat Biol 1997; 72(6):653-660.
  • [4]Taurin S,Seyrantepe V,Orlov SN,Tremhlay TL,Thibault P,Bennett MR,Hamet P,Pshezhetsky AV.Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of[Na+]i/[K+]i ratio in cultured vascular smooth muscle cells.Circ Res 2002; 91(10):915-922.
  • [5]Yang L,Liu X,Hao J,Yang Y,Zhao M,Zuo J,Liu W.Glucose-regulated protein 75 suppresses apoptosis induced by glucose deprivation in PC12 cells through inhibition of Bax conformational change.Acta Biochim Biophys Sin(Shanghai)2008; 40(4):339-348.
  • [6]Stetler RA,Gan Y,Zhang W,Liou AK,Gao Y,Can G,Chen J.Heat shock proteins:cellular and molecular mechanisms in the central nervous system.Prog Neurohiol 2010; 92(2):184-211.
  • [7]Richter K,Haslbeck M,Buchner J.The heat shock response:life on the verge of death.Mol Cell 2010; 40(2):253-266.
  • [8]Keshct Y,Seger R.The MAP kinase signaling cascades:A system of hundreds of components regulates a diverse array of physiological functions.Methods Mol Biol 2010; 661(1):3-38.
  • [9]Caunt C J,Finch AR,Sedgley KR,Oaklcy L,Luttrell LM,McArdle CA.Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors:receptor-specific activation mechanisms and compartmentalization.J Biol Chem 2006; 281(5):2701-2710.
  • [10]Chen DB,Davis JS.Epidermal growth factor induces c-fos and c-jnn mRNA via Raf-1/MEK1/ERK-dependent and-independent pathways in bovine luteal cells.Mol Cell Endocrinol 2003; 200(12):141-154.
  • [11]Harada H,Quearry B,Ruiz-Vela A,Korsmeyer SJ.Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM,inhibiting its association with BAX and proapoptotic activity.Proc Natl Acad Sci U S A 2004;101(43):15313-15317.
  • [12]Boulton TG,Nye SH,Robbins DJ,Ip NY,Radziejewska E,Morgenbesser SD,DePinho RA,Panayotatos N,Cobb MH,Yancopoulos GD.ERKs:a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.Cell 1991; 65(4):663-675.
  • [13]Kyosseva SV.Mitogen-activated protein kinase signaling.Int Rev Neurobiol 2004; 59:201-220.
  • [14]Favata MF,Horiuchi KY,Manos E J,Daulerio AJ,Stradley DA,Feeser WS,Van Dyk DE,Pitts W J,Earl RA,Hobbs F,Copeland RA,Magolda RL,Scherle PA,Trzaskos JM.Identification of a novel inhibitor of mitogen-activated protein kinase kinase.J Biol Chem 1998; 273(29):18623-18632.
  • [15]Boucher MJ,Morisset J,Vachon PH,Reed JC,Lainé J,Rivard N.MEK/ERK signaling pathway regulates the expression of Bcl-2,Bcl-X(L),and Mcl-1 and promotes survival of human pancreatic cancer cells.J Cell Biochem 2000; 79(3):355-369.
  • [16]Shi L,Wang S,Zangari M,Xu H,Cao TM,Xu C,Wu Y,Xiao F,Liu Y,Yang Y,Salama M,Li G,Tricot G,Zhan F.Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.Oncotarget 2010; 1(1):22-33.
  • [17]Luchetti F,Betti M,Canonico B,Arcangeletti M,Ferri P,Galli F,Papa S.ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells.Free Radic Biol Med 2009; 46(3):339-351.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn