Overexpression of β1-adrenoceptor can not protect rat cardiomyocytes from injury induced by isoprenaline

( views:52, downloads:0 )
Author:
WANG Ying()
ZHOU Feng()
XU Chuan-Ying()
SUN Hong()
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 62, Issue 06, 2010
DOI:
Key Word:

Abstract:

  • [1]Bristow MR,Minobe WA,Raynolds MV,Port JD,Rasmussen R,Ray PE,Feldman AM.Reduced beta 1 receptor messenger RNA abundance in the failing human heart.J Clin Invest 1993;92(6):2737-2745.
  • [2]Bristow MR,Ginsburg R,Umans V,Fowler M,Minobe W,Rasmussen R,Zera P,Menlove R,Shah P,Jamieson S,Stinson EB.Beta 1-and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium:coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.Circ Res 1986;59(3):297-309.
  • [3]Kiuchi K,Shannon RP,Komamura K,Cohen DL Bianchi C,Homey C J,Vatner SF,Vamer DE.Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure.J Clin Invest 1993;91(3):907-914.
  • [4]Sun H (孙红),Chang AM,Zhang Y,Wang Y,Xu YL,Chen Q.Overexpression of β1-adrenoceptors improves the contraction function in rat heart failure ventricular myocytes.Acta Univ Med Nanjing (南京医科大学学报) 2007;27(12):1398-1402 (Chinese,English abstract).
  • [5]Drazner MH,Peppel KC,Dyer S,Grant AO,Koch WJ,Lefkowitz RJ.Potentiation of beta-adrenergic signaling by adenoviral-mediated gene transfer in adult rabbit ventricular myocytes.J Clin Invest 1997;99(2):288-296.
  • [6]Sun H,Zhou F,Wang Y,Zhang Y,Chang A,Chen Q.Effects of beta-adrenoceptors overexpression on cell survival are mediated by Bax/Bcl-2 pathway in rat cardiac myocytes.Pharmacology 2006;78(2):98-104.
  • [7]McConville P,Spencer RG,Lakatta EG.Temporal dynamics of inotropic,chronotropic,and metabolic responses during betal-and beta2-AR stimulation in the isolated,perfused rat heart.Am J Physiol Endocrinol Metab 2005;289(3):E412-E418.
  • [8]del Monte F,Kaumann AJ,Poole-Wilson PA,Wynne DG,Pepper J,Harding SE.Coexistence of functioning beta 1-and beta 2-adrenoceptors in single myocytes from human ventricle.Circulation 1993;88(3):854-863.
  • [9]Summers RJ,Kompa A,Roberts SJ.Beta-adrenoceptor subtypes and their desensitization mechanisms.J Auton Pharmacol 1997;17(6):331-343.
  • [10]Lefkowitz RJ.G protein-coupled receptors.III.New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization.J Biol Chem 1998;273(30):18677-18680.
  • [11]Hausdorff WP,Caron MG,Lefkowitz RJ.Turning off the signal:desensitization of beta-adrenergic receptor function.FASEB J 1990;4(11):2881-2889.
  • [12]Saito S,Hiroi Y,Zou Y,Aikawa R,Toko H,Shibasaki F,Yazaki Y,Nagai R,Komuro I.beta-Adrenergic pathway induces apoptosis through calcineurin activation in cardiac myocytes.J Biol Chem 2000;275(44):34528-34533.
  • [13]Wang W,Zhu W,Wang S.Sustained β1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway.Circ Res 2004;95(8):798-806.
  • [14]Zhu WZ,Wang SQ,Chakir K.Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.J Clin Invest 2003;111(5):617-625.
  • [15]Morisco C,Zebrowski DC,Vatner DE.Beta-adrenergic cardiac hypertrophy is mediated primarily by the beta (1)-subtype in the rat heart.J.Mol Cell Cardiol 2001;33(3):561-573.
  • [16]Xiao RP,Zhu WZ,Zheng M.Subtype-specific α1 and β-adrenoceptor signaling in the heart.Trends Pharmacol Sci 2006;27(6):330-337.
  • [17]Communal C,Colucci WS.The control of cardiomyocyte apoptosis via the beta-adrenergic signaling pathways.Arch Mal Coeur Vaiss 2005;98(3):236-241.
  • [18]Xiao RP,Lakatta EG.β1-adrenoceptor stimulation and β2-adrenoceptor stimulation differ in their effects on contraction,cytosolic Ca2+,and Ca2+ current in single rat ventricular cells.Circ Res 1993;73(2):286-300.
  • [19]Sosunov EA,Gainullin RZ,Moise NS.β1 and β2-adrenergic receptor subtype effects in German shepherd dogs with inherited lethal ventricular arrhyflmfias.Cardiovasc Res 2000;48(2):211-219.
  • [20]Sun H(孙红),Chang AM,Zhang Y,Jiang XW.Effects of overexpression of β2-adrenoceptor on contraction in cardiac myocytes isolated from failure hearts of rats.Chin J Appl Physiol(中国应用生理学杂志)2007;23(4):410-414(Chinese,Engfish abstract).
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn