Suppression of nicotinic ACh receptors-mediated currents by activation of Eph/Ephrin-B1 signaling involves Src tyrosine kinase and mitogen-activated protein kinase in ciliary ganglion neurons

( views:, downloads: )
Author:
XIA Yuan-Peng()
HU Bo()
ZHOU Yu-Nan()
MAO Ling()
DAI Ruo-Lian()
DONG Li-Ping()
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 60, Issue 04, 2008
DOI:
Key Word:

Abstract:

  • [1]Hu B (胡波),Xia YP,Zhou YN,Dai RL,Dong LP,Mao L.Effects of EphB/Ephrin-B1 signal on the currents of alpha7-nAChRs on ciliary ganglion neurons.Acta Anatomica Sin (解剖学报) (in press,Chinese,English abstract).
  • [2]Pasquale EB.Eph receptors signaling casts a wide net on cell behavior.Nat Rev Mol Cell Biol 2005; 6(6):462-475.
  • [3]Murai KK,Pasquale EB.New exchanges in eph-dependent growth corn dynamics.Neuron 2005; 46(2):161-163.
  • [4]Goldshmit Y,McLenachan S,Turnley A.Roles of Eph receptors and Ephrins in the normal and damaged adult CNS.Brain Res Rev 2006; 52(2):327-345.
  • [5]Brückner K,Pasquale EB,Klein R.Tyrosine phosphorylation of transmembrane ligands for Eph receptors.Science1997; 275(5306):1640-1643.
  • [6]Nai Q,Mclntosh JM,Margiotta IF.Relating neuronal nicotinic acetylcholine receptors subtypes defined by subunit composition and channel function.Mol Pharmacol 2003; 63(2):311-324.
  • [7]Dalva MB,Takasu MA,Lin MZ,Shamah SM,Hu L,Gale NW,Greenberg ME.EphB receptors interact with NMDA receptors and regulate excitatory synapse formation.Cell 2000; 103(6):945-956.
  • [8]Cufforth T,Harrison C.Ephs and ephrins close ranks.Trends Neurosci 2002; 25(7):332-334.
  • [9]Bundesen LQ,Scheel TA,Bregrnan BS,Kromer LF.Ephrin-B2 and EphB2 regulation of astrocyte-meningeal fibroblast interactions in response to spinal cord lesions in adult rats.J Neurosci 2003; 23(21):7789-7800.
  • [10]Bums AL,Benson D,Howard MJ,Margiotta JF.Chick ciliary ganglion neurons contain transcription coding for acetylcholine receptors-associated protein at synapses.J Neurosci 1997; 17(13):5016-5026.
  • [11]Conroy WG,Liu Z,Nai Q,Coggan JS,Berg DK.PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons.Neuron 2003; 38(5):759-771.
  • [12]Thomas GM,Huganir RL.MAPK cascade signaling and synaptic plasticity.Nat Rev Neurosci 2004; 5(3):173-183.
  • [13]Charpantier E,Wiesner A,Huh KH,Ogier R,Hoda JC,Allaman G,Raggenbass M,Feuerbach D,Bertrand D,Fuhrer C.α7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and src-family kinases.J Neurosci 2005; 25(43):9836-9849.
  • [14]Vindis C,Cerretti DP,Daniel TO,Huynh-Do U.EphB1 recruits c-Src and p52shc to activate MAPK/ERK and promote chemotaxis.J Cell Biol 2003; 162(4):661-671.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn