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Imaging the neuromuscular junction over the past centuries

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Author:
No author available
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
6
DOI:
No doi available
Key Word:
神经肌肉接头;成像技术;N型乙酰胆碱受体;突触小泡释放;发育;neuromuscularjunction;imaging technique;nicotinic acetylcholine receptor;synaptic vesicle release;development

Abstract: The neuromuscularjunction(NMJ)has been studied for over a century as a model system for synaptic anatomy,physiology and development.Much of our knowledge of the NMJ has been obtained through imaging techniques,some of which were developed particularly to visualize this synapse's structure and function.In this paper we review the historical development of research on some key aspects of the NMJ,including its structure,nicotinic acetylcholine receptor distribution,the process of synaptic vesicle release,and its development.

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