Spotlight on cardioprotection against ischemia-reperfusion injury

( views:, downloads: )
Author:
YANG Huang-Tian(YANG Huang-Tian,Dr. YANG Huang-Tian received her B.S. in Medicine in 1982 from Nantong University School of Medicine and M.S. in Medicine in 1988 from Suzhou University School of Medicine. Then she received her Ph.D. from Yamagata University School of Medicine,Japan in 1994, and served as a faculty member in the Department of Pharmacology there up to 1997. In the same year, she moved to NIH/NIA to continue her research on cardiac receptors and signaling regulation and took current position since 2000. Dr. YANG is members of the Standing Committees of Chinese Association for Physiological Sciences, Chinese Association of Pathophysiology in Cardiovascular Sciences and in Receptors and Signal Transduction, the International Society for Heart ResearchChina Section, and Chinese Society of High )
TANG Chao-Shu(TANG Chao-Shu,Dr. TANG Chao-Shu received his B.S. degree in medicine in 1968 and M.S. degree in Pathophysiology in 1981 from Beijing Medical College, respectively. As a visiting scholar he moved to Saint Louis University to continue his research work during 1985.6-1986.7,1989.5-1990.5, 1993.3-1994.10, 1997.8-1998.4, respectively. He was promoted to be a professor in 1990 and to be a post-student supervisor in 1993, respectively. Professor TANG has been engaged in teaching and research work of physiological and pathological mechanisms of cardiovascular system. The long-term goal of Professor TANG's laboratory is to be elucidating vasoactive peptide mechanisms of cardiovascular disease pathogenesis and cellular protection mechanisms against cardiovascular diseases. He was a chief scientist o)
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 59, Issue 05, 2007
DOI:
Key Word:

Abstract´╝Ü

  • [1]Hausenloy DJ,Yellon DM.Preconditioning and postconditioning:United at reperfusion.Pharmacol Ther 2007; 116:173-191.
  • [2]Murry CE,Jennings RB,Reimer KA.Preconditioning with ischemia:a delay of lethal cell injury in ischemic myocardium.Circulation 1986; 74:1124-1136.
  • [3]Liu GS,Thornton J,Van Winkle DM,Stanley AWH,Olsson RA,Downey JM.Protection against infarction afforded by preconditioning is mediated by Al adenosine receptors in rabbit heart.Circulation 1991; 84:350-356.
  • [4]Zhao ZQ,Corvera JS,Halkos ME,Kerendi F,Wang NP,Guyton RA,Vinten-Johansen J.Inhibition of myocardial injury by ischemic postconditioning during reperfusion:comparison with ischemic preconditioning.Am J Physiol Heart Circ Physiol 2003; 285:H579-H588.
  • [5]Xu Z,Yang XM,Cohen MV,Neumann T,Heusch G,Downey JM.Limitation of infarct size in rabbit hearts by the novel adenosine receptor agonist AMP 579 administered at reperfusion.J Mol Cell Cardiol 2000; 32:2339-2347.
  • [6]Szekeres L.Drug-induced delayed cardiac protection against the effects of myocardial ischemia.Pharmacol Ther 2005; 108:269-280.
  • [7]Przyklenk K,Darling CE,Dickson EW,Whittaker P.Cardioprotection 'outside the box'--the evolving paradigm of remote preconditioning.Basic Res Cardiol 2003; 98:149-157.
  • [8]Asemu G,Papousek F,Ostadal B,Kolar F.Adaptation to high altitude hypoxia protects the rat heart against ischemia-induced arrhythmias.Involvement of mitochondrial KATP channel.J Mol Cell Cardiol 1999; 31:1821-1831.
  • [9]Zhu WZ,Xie Y,Chen L,Yang HT,Zhou ZN.Intermittent high altitude hypoxia inhibits opening of mitochondrial permeability transition pores against reperfusion injury.J Mol Cell Cardiol 2006; 40:96-106.
  • [10]Yellon DM,Opie LH.Postconditioning for protection of the infarcting heart.Lancet 2006; 367:456-458.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn