Biological effects of toosendanin, an active ingredient of herbal vermifuge in Chinese traditional medicine

( views:, downloads: )
Author:
SHI Yu-Liang()
WANG Wen-Ping()
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 58, Issue 05, 2006
DOI:
Key Word:

Abstract:

  • [1]Shi YL.Toosendanin,a new presynaptic blocker.In "Study and Utility of Toxins".Chen YC,Yuan SL.eds.Beijing:Science Press,1988,192-206.
  • [2]Shi YL.Chinaberry and toosendanin.In "Exploitation and Utility of Biotoxins".Liu DY.ed.Beijing:Chemical Industrial Press,2006.
  • [3]Zhong CC (钟炽昌),Hsie TH,Chen SF,Liang HT.The structure of Chuanliansu.Acta Chim Sin (化学学报) 1975; 33:35-47 (Chinese,English abstract).
  • [4]Shu GX (舒国欣),Liang XT.A correction of the structure of Chuanliansu.Acta Chim Sin (化学学报) 1980; 38:196-198(Chinese,English abstract).
  • [5]Shi YL (施玉樑),Wei NS,Yang YQ,Wang ZX.Toosendanin-a presynaptic neuromuscular blocking agent.Acta Physiol Sin(生理学报) 1980; 32:293-297 (Chinese,English abstract).
  • [6]Shi YL,Wang ZF.Cure of experimental botulism and antibotulismic effect of toosendanin.Acta Pharmacol Sin 2004;25:839-848.
  • [7]Shi YL (施玉樑),Tang MZ.Cell death and apoptosis-induced effect of toosendnin.Chin J Neurosci (中国神经科学杂志) 2004; 20:461-465 (Chinese,English abstract).
  • [8]Li MF,Shi YL.Toosendanin,a triterpenoid derivative,acts as a novel agonist of L-type Ca2+ channels in neonatal rat ventricular cells.Eur J Pharmacol 2004; 501:71-78.
  • [9]Shi YL (施玉樑),Wang WP,Liao CY,Chiu SH.Effect of toosendanin on the sensory inputs of chemoreceptors in the armyworm larvae (Mythimne Separata).Atca Entomal Sin (昆虫学报) 1986; 29:233-239 (Chinese,English abstract).
  • [10]Chiu SF.Recent advances in research on botanical insecticides in China.In "Insecticides of Plant Origin".Arnason JT,Philogene B JR,Morand P.eds.Washington DC:American Chemical Society,1989,69-77.
  • [11]Carpinella MC,Defago MT,Valladares G,Palacios SM.Antifeedant and insecticide properties of a limonoid from Melia azedarach (Meliaceae) with potential use for pest management.J Agfic Food Chem 2003; 51:369-374.
  • [12]Zhang X (张兴),Wang XL,Feng JT,Chiu SF.The development of botanical insecticides-toosendanin.Acta Univ Agric Boreali-occidentalis (西北农业大学学报) 1993; 21:1-5(Chinese,English abstract).
  • [13]Wang YB (王荫碧),Wen YX.A comprehensive report on clinic ascarid anthelminthictherepeutic effect of toosendanin pills.J Trad Chin Med (中医杂志) 1959; 262:46-49(Chinese).
  • [14]Sun BY (孙步云).Two kulianpian poisoning cases.J Trad Chin Med (中医杂志) 1958; 261:401-402 (Chinese).
  • [15]Yang P (杨平),Li CS.Chuanlianpian-induced poisoning of pigs.China Anim Husb Vet Med (中国畜牧兽医) 1962; 7:25-26 (Chinese).
  • [16]Randic M,Straughan DW.Antidromic activity in the rat phrenic nerve-diaphragm preparation.J Physiol 1964; 173:130-148.
  • [17]Huang SK (黄世揩),Song XE,Shi YL.Effects of toosendanin on the fine structure of the mouse neuromuscular junction.Acta Physiol Sin (生理学报)1980; 32:385-390 (Chinese,English abstract).
  • [18]Xiong CS (熊春生).Effect of toosendanin on the ultrastructure of the rat neuromuscular junction.Acta Pharm Sin (药学学报) 1982; 17(6):407-412 (Chinese,English abstract).
  • [19]Clark AW,Hurlbut WP,Mauro A.Changes in the fine structure of neuromuscular junction of the frog caused by black widow spider venom.J Cell Biol 1972; 52:1-14.
  • [20]Xiong CS (熊春生).The interaction between toosendanin and botulinum toxin at the neuromuscular junction,an ultrastructral observation.Acta Pharm Sin (药学学报) 1985;20(7):495-499 (Chinese,English abstract).
  • [21]Shi YL (施玉樑),Wang WP,Xu K.Electrophysiological analysis on the presynaptic blocking effects of toosendanin on neuromuscular transmission.Acta Physiol Sin (生理学报)1981; 33:259-265 (Chinese,English abstract).
  • [22]Shi YL (施玉樑),Yang YQ,Wang WP,Xu K.Influence of stimulus frequency,temperature and Ca2+ on onset of toosendanin paralysis of isolated neuromuscular preparations of rats.Acta Physiol Sin (生理学报) 1981; 33:141-146(Chinese,English abstract).
  • [23]Shi YL (施玉樑),Wang WP,Yan SQ,Xu K.Effects of calcium ions and nerve impulses on changes in miniature endplate potential frequency produced by toosendanin.Acta Physiol Sin (生理学报) 1982; 34:304-309 (Chinese,English abstract).
  • [24]Katz B,Miledi R.Transmitter leakage from motor nerve endings.Proc R Soc (B) 1977; 196:59-72.
  • [25]Vyskocil F,Nikolsky E,Edwards C.A non-quantal release of acetylcholine at the mouse neuromuscular junction.Neuroscience 1983; 9:429-435.
  • [26]Shi YL.Abolishment of non-quantal release of acetylcholine from the mouse phrenic nerve ending by toosendanin.Jap J Physiol 1986; 33:677-680.
  • [27]Zou J (邹镜).A study on pharmacokinetics of toosendanin.Chin Trad Herb Drugs (中草药) 1982; 13:24-26 (Chinese).
  • [28]Shi YL,Chen WY.Effect of toosendanin on acetylcholine release from rat brain,a microdialysis study.Brain Res 1999;850:173-178.
  • [29]Chen WY,Yin PB,Ye WL,Shi YL.Toosendanin-induced change of dopamine level detected by microdialysis in vivo at rat striatum.Chin Sci Bull 1999; 44:1106-1110.
  • [30]Huang HY,Zhou CW,Shi YL.Toosendanin facilitates[3H]noradrenaline release from rat hippocampal slices.Nat Toxins 1996; 4:92-95.
  • [31]Xu TH,Shi YL,Ren XM,Zhou JY.Inhibition of glutamate release from rat cerebral synaptosomes by a prejunctional blocker toosendanin.Chin J Pharmacol Toxicol (中国药理学与病理学杂志) 2004; 18:321-326.
  • [32]Zhao WQ,Feng H,Bennett P,Ng KT.Inhibition of intermediate-term memory following passive avoidance training in neonate chicks by a presynaptic cholinergic blocker.Neurobiol Learn Mem 1997; 67:207-213.
  • [33]Li MF,Shi YL.The long-term effect of toosendanin on current through nifedipine-sensitive Ca2+ channels in NG 108-15cells.Toxicon 2005; 45:53-60.
  • [34]Cui ZJ,He XH.The pre-synaptic blocker toosendanin does not inhibit secretion in exocrine cells.World J Gastroenterol 2002; 8:918-922.
  • [35]Li PZ (李培忠) Zhou J,Miao WY,Ding FH,Meng JY,Jia GR,Li JF,Ye H J,He XY,Chen MY,Huang ZM.Therapeutic effect of toosendanin on animal botulism.Chin Trad Herb Drugs (中草药) 1982; 13:28-30 (Chinese).
  • [36]Zou J,Miao WY,Ding FH,Meng JY,Ye HJ,Jia GR,He XY,Sun GZ,Li PZ.The effect of toosendanin on monkey botulism.J Trad Chin Med 1985; 5:29-30.
  • [37]Shi YL (施玉樑),Xu K.Antibotulismic effect of toosendanin.Chin Sci Bull (科学通报) 1983; 28:885-887 (Chinese).
  • [38]Li PZ (李培忠),Sun GZ.Antibotulismic effect of toosendanin to botulinum toxins on neuromuscular preparations of mice.Acta Physiol Sin (生理学报)1983; 35:480-483 (Chinese,English abstract).
  • [39]Shi YL,Xu K.Anti-botulismic effect of toosendanin and its facilitatory action on miniature end-plate potentials.Jap J Physiol 1983; 33:677-680.
  • [40]Sathyamoorthy V,DasGupta BR.Separation,purification,partial characterization and comparison of the heavy and light chains of botulinum neurotoxin types A,B,and E.J Biol Chem 1985; 260:10461-10466.
  • [41]Simpson LL.Botulinum neurotoxin and tetanus toxin.San Diego:Academy Press,1989.
  • [42]Shi YL (施玉樑),Sun LQ.Selective binding of toosendanin to synaptosome fraction from rat brain.Acta Physiol Sin (生理学报) 1982; 34:211-216 (Chinese,English abstract).
  • [43]Shen GG (沈国光),Zhuo XL,Sh,YL.The binding sites of 3H-toosendanin in rat cerebral cortex homogenate.Acta Physiol Sin (生理学报) 1994; 46:546-552 (Chinese,English abstract).
  • [44]Zhou JY,Wang ZF,Ren XM,Tang MZ,Shi YL.Antagonism of botulinum toxin type A-induced cleavage of SNAP-25 in rat cerebral synaptosome by toosendanin.FEBS Lett 2003;555:375-379.
  • [45]Zhou JY,Shi YL.Inhibition of botulinum toxin's association with rat brain synaptosomes by toosendanin,an antibotulismic triterpenoid.Nerve Regen Res 2006; in press.
  • [46]Blaustein RO,Germann WJ,Finkelstein A,DasGupta BR.The N-terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayers.FEBS Lett 1987; 226:115-120.
  • [47]Donovan JL Middlebrook JL.Ion-conducting channels produced by botulinum toxin in planar lipid membranes.Biochemistry 1986; 25:2872-2876.
  • [48]Hoch DH,Romero-Mira M,Ehrlich BE,Finkelstein A,Dasgupta BR.Channels formed by botulinum,tetanus,and diphtheria toxins in planar lipid bilayers:relevance to translocation of proteins across membranes.Proc Natl Acad Sci USA 1985; 82:1692-1696.
  • [49]Koriazova LK,Montal M.Translocation of botulinum neurotoxin light chain protease through the heavy chain channel.Nat Struct Biol 2003; 10:13-18.
  • [50]Li MF,Shi YL.Toosendanin inhibits pore formation of botulinum toxin type A at PC12 cell membrane.Acta Pharmacol Sin 2006; 27:66-70.
  • [51]Chen WY (陈文雁),Shi YL.The.morphological changes induced by toosendanin on NG108-15 cells and S K-N-SH cells.Chin J Anat (解剖学报) 2000; 23:1-5 (Chinese,English abstract).
  • [52]Tang MZ,Wang ZF,Shi YL.Toosendanin induces outgrowth of neuronal processes and apoptosis in PC 12 cells.Neuronsci Res 2003; 45:225-231.
  • [53]Yu JC,Min ZD,Ip NY.Melia toosendan regulates PC12 cell differentiation via the activation of protein kinase A and extracellular signal-regulated kinases.Neurosignals 2004; 13:248-257.
  • [54]Tang MZ,Wang ZF,Shi YL.Involvement of cytochrome c release and caspase activation in toosendanin-induced apoptosis of PC12 cells.Toxicology 2004; 201:31-38.
  • [55]Zhang B.Wang ZF,Tang MZ,Shi YL.Growth inhibition and apoptosis-induced effect on human cancer cells of toosendanin,a triterpenoid derivative from Chinese traditional medicine.Invest New Drugs 2005; 23:547-553.
  • [56]Shi YL,Furuya K,Wang WP,Terakawa S,Xu K,Yamagishi S.Toosendanin-induced Ca2+ conductance increase in neuroblastoma×glioma hybrid cells.Chin Sci Bull 1993; 38:1489-1493.
  • [57]Xu TH,Ding J,Shi YL.Toosendanin increased free-Ca2+ concentration in NG108-15 cells via L-type Ca2+ channels.Acta Pharmacol Sin 2004; 25:597-601.
  • [58]Li MF,Wu Y,Wang ZF,Shi YL.Toosendanin,a triterpenoid derivative,increases Ca2+ current in NG108-15 cells via L-type channels.Neurosci Res 2004; 49:197-203.
  • [59]Nattson MP,Kater SB.Calcium regulation of neurite elongation and growth cone motility.J Neurosci 1987; 7:4034-4043.
  • [60]Nattson M,Taylor-Hunter A,Skater S.Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP.J Neurosci 1988; 8:1704-1711.
  • [61]Szalai G,Krishramuthy R,Hajnoezky G.Apoptosis driven by IP3-1inked mitochondria calcium signals.EMBO J 1999; 18:6349-6361.
  • [62]Hajnoczky G,Davies E,Madesh M.Calcium signaling and apoptosis.Biochem Biophysic Res Commun 2003; 304:445-454.
  • [63]Mallart A.Presynaptic currents in frog motor endings.Pflugers Arch 1984; 400:8-13.
  • [64]Xu YF,Shi YL.Action of toosendanin on the membrane current of motor nerve terminals.Brain Res 1993; 631:46-50.
  • [65]Hu Q,Huang FS,Shi YL.Inhibition of toosendanin on the delayed rectifier potassium current in neuroblastoma×glioma NG108-15 cells.Brain Res 1997; 751:47-53.
  • [66]Wang ZF,Shi YL.Inhibition of large-conductance Ca2+-activated K+ channel in hippocampal neurons by toosendanin.Neuroscience 2001; 104:41-47.
  • [67]Wang ZF,Shi YL.Toosendnin-induced inhibition of smallconductance calcium-activated potassium channels in CA1 pyramidal neurons of rat hippocampus.Neurosci Lett 2001;30:313-316.
  • [68]Wang ZF,Shi YL.Modulation of inward rectifier potassium channel by toosendanin,a presynaptic blocker.Neurosci Res 2001; 40:211-215.
  • [69]Gao XD,Tang SB,Lu J,Shi YL.Effects of toosendanin on electric and mechanical properties of guinea pig papillary muscles.Acta Pharmacol Sin 1994; 15:147-151.
  • [70]Ding J,Xu TH,Shi YL.Different actions of toosendanin on perineuriaily recorded Ca2+ currents in mouse and frog motor nerve terminals.Neurosci Res 2001; 41:243-249.
  • [71]Li M (李玫),Song JZ.Chinaberry seeds combined with synthesized therapeutics save patients from botulism.Chin J Crit Care Med (疑难症护理杂志) 2003; 23:718 (Chinese).
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn