Protective effect of sevoflurane preconditioning on oxygen-glucose deprivation injury in rat hippocampal slices: the role of mitochondrial KATP channels

( views:, downloads: )
WANG Zhi-Ping()
ZHANG Zhao-Hang()
ZENG Yin-Ming()
JIANG Shan()
WANG Shu-Qu()
WANG Sheng()
Journal Title:
Volume 58, Issue 03, 2006
Key Word:


  • [1]Matei G,Pavlik R,McCadden T,Cottrell JE,Kass IS.Sevoflurane improves electrophysiological recovery of rat hippocampal slice CA1 pyramidal neurons after hypoxia.J Neurosurg Anesthesiol 2002;14(4):293-298
  • [2]Kehl F,Payne RS,Roewer N,Schurr A.Sevoflurane-induced preconditioning of rat brain in vitro and the role of KATP channels.Brain Res 2004;1021(1):76-81
  • [3]Wise-Faberowski L,Raizada MK,Sumners C.Desflurane and sevoflurane attenuate oxygen and glucose deprivation-induced neuronal cell death.J Neurosurg Anesthesiol 2003;15(3):193-199
  • [4]Kapinya KJ,Lowl D,Futterer C,Maurer M,Waschke KF,Isaev NK,Dirnagl U.Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent.Stroke 2002,33(7):1889-1898
  • [5]Xiong L,Zheng Y,Wu M,Hou L,Zhu Z,Zhang X,Lu Z.Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphateregulated potassium channels after focal cerebral ischemia in rats.Anesth Analg 2003;96(1):233-237
  • [6]Toner CC,Connelly K,Whelpton R,Bains S,Michael-Titus AT,McLaughlin DP,Stamford JA.Effect of sevoflurane on dopamine,glutamate and aspartate release in an in vivo model of cerebral ischaemia.Brit J Anaes 2001;86(4):550-554
  • [7]Cope DK,Impastato WK,Cohen MV,Downey JM.Volatile anesthetics protect the ischemic rabbit myocardium from infarction.Anesthesiology 1997;86(3):699-709
  • [8]Zhao P,Zuo Z.Isoflurane preconditioning induces neuroprotection that is indtcible nitric oxide synthase-dependent in neonatal rats.Anesthesiology 2004;101(3):695-703
  • [9]Toller WG,Montgomery MW,Pagel PS,Hettrick DA,Warltier DC,Kersten JR.Isoflurane-enhanced recovery of canine stunned myocardium:role for protein kinase C? Anesthesiology 1999;91(3):713-722
  • [10]Gross GJ,Auchampach JA.Role of ATP dependent potassium channels in myocardial ischaemia.Cardiovasc Res 1992;26(11):1011-1016
  • [11]Schulz R,Cohen MV,Behrends M,Downey JM,Heusch G.Signal transduction of ischemic preconditioning.Cardiovasc Res 2001;52(2):181-198
  • [12]Bajgar R,Seetharaman S,Kowaltowski A J,Garlid KD,Paucek P.Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain.J Biol Chem 2001;276(36):33369-33374
  • [13]Shimizu K,Lacza Z,Rajapakse N,Horiguchi T,Snipes J,Busija DW.mitoKATP opener,diazoxide,reduces neuronal damage after middle cerebral artery occlusion in the rat.Am J Physiol Heart Circ Physiol 2002;283(3):H1005-H1011
  • [14]Pomerantz B J,Robinson TN,Heimbach JK,Calkins CM,Miller SA,Banerjee A,Harken AH.Selective mitochondrial KATP channel opening controls human myocardial preconditioning:too much of a good thing? Surgery 2000;128(2):368-373
  • [15]Ghosh S,Standen NB,Galinanes M.Evidence for mitochondrial KATP channels as effectors of human myocardial preconditioning.Cardiovasc Res 2000;45(4):934-940
  • [16]Gross GJ.The role of mitochondrial KATP channels in cardioprotection.Basic Res Cardiol 2000;95(4):280-284
  • [17]Crawford MW,Lerman J,Saldivia V,Carmichael FJ.Hemodynamic and organ blood flow responses to halothane and sevoflurane anesthesia during spontaneous ventilation.Anesth Analg 1992;75(6):1000-1006
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615