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Developmental regulation of intracellular calcium homeostasis in early cardiac myocytes

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Author:: No author available

Journal Title:: ACTA PHYSIOLOGICA SINICA

Issue:: 2

DOI:: 10.3321/j.issn:0371-0874.2006.02.001

Key Word:: 钙稳态;心肌细胞;分化发育;Ca2+ homeostasis;cardiomyocytes;development

Abstract： The proper intracellular Ca2+ signaling is essential for normal cell functions and organ development, and the maintaining Ca2+ homeostasis in cardiac myocytes is of functional importance for the intact heart. As the first functional organ in the vertebrate embryo,the heart is continuously remodeled and maintains its physiologic pumping function in response to increasing circulatory demands. The expressions of Ca2+ handing proteins in the embryonic heart, however, are different from those in neonatal and adult hearts, which means that the regulation of Ca2+ transients in embryonic cardiomyocytes is different from that in adult cardiac myocytes. Recent advances in molecular and cellular biology, as well as the application of embryonic stem cell differentiation system, have made progress in uncovering the regulation of Ca2+ homeostasis during cardiomyogenesis. This paper briefly summarizes the Ca2+ homeostasis during early development of cardiomyocytes and reviews current knowledge of the regulatory mechanisms controlling Ca2+ homeostasis during cardiomyocyte development.

Reference

[1]S V, Koushik,J, Wang,R, Rogers,etc.Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.[J].2001,15.
[2]Yasui K,Kodama I,Liu W,etc.Developmental changes of Ca(2+) handling in mouse ventricular cells from early embryo to adulthood.[J].2002,71(11).
[3]J, Hescheler,B K, Fleischmann,S, Lentini,etc.Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis.[J].1997,36.
[4]T, Saeki,J B, Shen,A J, Pappano.Inositol-1,4,5-trisphosphate increases contractions but not L-type calcium current in guinea pig ventricular myocytes.[J].1999,41.
[5]D, Orlic,J, Kajstura,S, Chimenti,etc.Bone marrow cells regenerate infarcted myocardium.[J].2001,410(6829).
[6]Zhang Ying Ming,Shang Lijuan,Hartzell Criss,etc.Characterization and regulation of T-type Ca2+channels in embryonic stem cell-derived cardiomyocytes[J].2003.
[7]STEPHAN E. LEHNART,WOLFGANG SCHILLINGER,BURKERT PIESKE,etc.Sarcoplasmic Reticulum Proteins in Heart Failure[J].1998,853(1).
[8]Arai A,Liu W,Kamiya K,etc.beta-adrenergic modulation of L-type Ca2+-channel currents in early-stage embryonic mouse heart.[J].1999,276(2 Pt.2).
[9]Chin O. Lee,Chung-Hyun Cho,Myung-jin Jeong,etc.The Na~+-Ca~(2+) Exchanger Is Essential for Embryonic Heart Development in Mice[J].2000,10(6).
[10]N, Tohse,J, Mészáros,N, Sperelakis.Developmental changes in long-opening behavior of L-type Ca2+ channels in embryonic chick heart cells.[J].1992,71.
[11]D M, Bers,E, Perez-Reyes.Ca channels in cardiac myocytes: structure and function in Ca influx and intracellular Ca release.[J].1999,42.
[12]K A, Dicker,B, L?wenberg,U W, Schaefer,etc.[Allogenic bone marrow transplantation in men].[J].1975,16.
[13]Mery A,Michalak M,Puceat M,etc.Initiation of embryonic cardiac pacemaker activity by inositol 1,4,5-trisphosphate-dependent calcium signaling[J].2005,16(5).
[14]M, L?hn,M, Fürstenau,V, Sagach,etc.Ignition of calcium sparks in arterial and cardiac muscle through caveolae.[J].2000,87.
[15]Zilberman A,Babu GJ,Wuytack F,etc.The expression of SR calcium transport ATPase and the Na(+)/Ca(2+)Exchanger are antithetically regulated during mouse cardiac development and in Hypo/hyperthyroidism.[J].2000,32(3).
[16]H, Masuda,K, Sumii,N, Sperelakis.Long openings of calcium channels in fetal rat ventricular cardiomyocytes.[J].1995,429(4).
[17]Maltsev V. A.,Ji G. J.,Wobus A. M.,etc.Establishment of\u00a0-Adrenergic Modulation of L-Type Ca2+ Current in the Early Stages of Cardiomyocyte Development[J].1999.
[18]Bers DM.Macromolecular complexes regulating cardiac ryanodine receptor function.[J].2004,37(2).
[19]Walsh RA,Lalli MJ,Kirkpatrick DL,etc.Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.[J].2000,275(48).
[20]Bloch W,Schwinger RH,Sugaru A,etc.Increased expression of isoform 1 of the sarcoplasmic reticulum Ca(2+)-release channel in failing human heart.[J].2001,103(22).
[21]T, Nakanishi,M, Seguchi,A, Takao.Development of the myocardial contractile system.[J].1988,44.
[22]Haddock PS,Coetzee WA,Artman M.Influence of postnatal changes in action potential duration on Na-Ca exchange in rabbit ventricular myocytes.[J].1998,435(6).
[23]Wobus AM,Boheler KR.Embryonic stem cells: prospects for developmental biology and cell therapy.[J].2005,85(2).
[24]J S, Sham,L, Cleemann,M, Morad.Gating of the cardiac Ca2+ release channel: the role of Na+ current and Na(+)-Ca2+ exchange.[J].1992,255(5046).
[25]M H, Soonpaa,G Y, Koh,M G, Klug,etc.Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium.[J].1994,264.
[26]S E, Litwin,J, Li,J H, Bridge.Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytes.[J].1998,75(1).
[27]E, Carafoli.Biogenesis: plasma membrane calcium ATPase: 15 years of work on the purified enzyme.[J].1994,8(13).
[28]Nora Rosemblit,Maria C. Moschella,Elena Ondriasova,etc.Intracellular Calcium Release Channel Expression during Embryogenesis[J].1999,206(2).
[29]A, Ribadeau-Dumas,M, Brady,S Y, Boateng,etc.Sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2) gene products are regulated post-transcriptionally during rat cardiac development.[J].1999,43.
[30]Mascareno E,Siddiqui MA,Ghatpande S,etc.Signal transduction and transcriptional adaptation in embryonic heart development and during myocardial hypertrophy.[J].1999,196(1).
[31]Y, Qu,A, Ghatpande,N, el-Sherif,etc.Gene expression of Na+/Ca2+ exchanger during development in human heart.[J].2000,45.
[32]Marks AR.Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death.[J].2001,33(4).
[33]C, Toyoshima,M, Nakasako,H, Nomura,etc.[Structure determination of the calcium pump of sarcoplasmic reticulum].[J].2001,46.
[34]Chen F,Ding S,Lee BS,etc.Sarcoplasmic reticulum Ca(2+)ATPase and cell contraction in developing rabbit heart.[J].2000,32(5).
[35]Hiroshi, Takeshima.Intracellular Ca2+ store in embryonic cardiac myocytes.[J].2002,7.
[36]Bassani Rosana A.,Bassani Jos\u00e9W. M..Contribution of Ca2+transporters to relaxation in intact ventricular myocytes from developing rats[J].2002.
[37]I.I. Serysheva,M. Schatz,M. van Heel,etc.Structure of the Skeletal Muscle Calcium Release Channel Activated with Ca2+ and AMP-PCP[J].1999,77(4).
[38]Hescheler J,Lindner M,Sauer H,etc.Characteristics of calcium sparks in cardiomyocytes derived from embryonic stem cells.[J].2001,281(1).
[39]Bers D M,Bridge J H,Spitzer K W.Intracellular Ca2+ transients during rapid cooling contractures in guinea-pig ventricular myocytes.[J].1989,417(1).
[40]Ji-Dong Fu,Li, Jun,Tweedie, David,etc.Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca<sup>2+</sup> transients and contraction in cardiomyocytes derived from embryonic stem cells.[J].2006,20(1).
[41]Hescheler J,Viatchenko Karpinski-S,Fleischmann BK,etc.Intracellular Ca2+ oscillations drive spontaneous contractions in cardiomyocytes during early development.[J].1999,96(14).
[42]Brand T..Heart development: molecular insights into cardiac specification and early morphogenesis [Review][J].2003,258(1).
[43]Nishimaru K.,Tanaka H.,Sekine T.,etc.Role of sarcoplasmic reticulum in myocardial contraction of neonatal and adult mice[J].1998,120(3).
[44]P, James,M, Maeda,R, Fischer,etc.Identification and primary structure of a calmodulin binding domain of the Ca2+ pump of human erythrocytes.[J].1988,263.
[45]Kitchens SA,Creazzo TL,Burch J.T-type Ca(2+) current contribution to Ca(2+)-induced Ca(2+) release in developing myocardium.[J].2003,35(5).
[46]Sedarat F,Tibbits GF,Xu L.Ontogeny of excitation-contraction coupling in the mammalian heart.[J].2002,132(4).
[47]Sipido KR,Van-de-Werf F,Carmeliet E.T-type Ca2+ current as a trigger for Ca2+ release from the sarcoplasmic reticulum in guinea-pig ventricular myocytes (see comments)[J].1998,508(Pt.2).
[48]T S, Klitzner,W F, Friedman.A diminished role for the sarcoplasmic reticulum in newborn myocardial contraction: effects of ryanodine.[J].1989,26.
[49]K D, Philipson,D A, Nicoll.Sodium-calcium exchange: a molecular perspective.[J].2000,62.
[50]Kubalak SW,Becker DK,Kass RS,etc.Differentiation of cardiomyocytes in floating embryoid bodies is comparable to fetal cardiomyocytes.[J].2000,32(5).
[51]J, Kocksk?mper,K A, Sheehan,D J, Bare,etc.Activation and propagation of Ca(2+) release during excitation-contraction coupling in atrial myocytes.[J].2001,81(5).
[52]W H, Barry,J H, Bridge.Intracellular calcium homeostasis in cardiac myocytes.[J].1993,87.
[53]D A, Nicoll,S, Longoni,K D, Philipson.Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger.[J].1990,250(4980).
[54]van Ginneken AC,Boheler KR,Christoffels VM,etc.Cardiomyocytes purified from differentiated embryonic stem cells exhibit characteristics of early chamber myocardium.[J].2003,35(12).
[55]L, Mahony,L R, Jones.Developmental changes in cardiac sarcoplasmic reticulum in sheep.[J].1986,261(32).
[56]A F, Moorman,J L, Vermeulen,M U, Koban,etc.Patterns of expression of sarcoplasmic reticulum Ca(2+)-ATPase and phospholamban mRNAs during rat heart development.[J].1995,76.
[57]Z, Zhou,C T, January.Both T- and L-type Ca2+ channels can contribute to excitation-contraction coupling in cardiac Purkinje cells.[J].1998,74(4).
[58]G T, Wetzel,T S, Klitzner.Developmental cardiac electrophysiology recent advances in cellular physiology.[J].1996,31 Spec No.
[59]M U, Koban,A F, Moorman,J, Holtz,etc.Expressional analysis of the cardiac Na-Ca exchanger in rat development and senescence.[J].1998,37.
[60]Yang HT,Tweedie D,Wang S,etc.The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development.[J].2002,99(14).
[61]Boutjdir M,Qu Y.Gene expression of SERCA2a and L- and T-type Ca channels during human heart development.[J].2001,50(5).
[62]Komazaki S,Noda T,Iino M,etc.Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.[J].1998,17(12).
[63]Iino M,Komazaki S,Nishi M,etc.Junctophilins: a novel family of junctional membrane complex proteins.[J].2000,6(1).
[64]M P, Davies,R H, An,P, Doevendans,etc.Developmental changes in ionic channel activity in the embryonic murine heart.[J].1996,78.
[65]M V, Westfall,K A, Pasyk,D I, Yule,etc.Ultrastructure and cell-cell coupling of cardiac myocytes differentiating in embryonic stem cell cultures.[J].1997,36(1).