Inhibitory effect of cholecystokinin-octapeptide on production of cytokines in the lung of endotoxic shock rats

( views:, downloads: )
Journal Title:
Volume 54, Issue 02, 2002
Key Word:


  • [1]Ling YL (凌亦凌),Huang SS (黄善生),Wang LF (王乐丰),Zhang JL(张君岚),Wan M(万梅),Hao RL(郝荣利).Cholecystokinin-octapeptide (CCK-8) reverses experimental endotoxin shock.Acta Physiol Sin (生理学报),1996,48(4):390~394 (Chinese,English abstract).
  • [2]Molina PE,Abumrad NN.Differential effects of hemorrhage and LPS on tissue TNF-α,IL-1 and associate neuro-hormonal and opioid alterations.Life Sci,2000,66:399~408.
  • [3]Schlag G,Redl H.Mediators of injury and inflammation.World J Surg,1996,20:406~410.
  • [4]Jansen MJJM,Hendriks T,Vogels MTE,Van der Meer JWM,Goris RJA.Inflammatory cytokines in an experimental model for the multiple organ dysfunction syndrome.Crit Care Med,1996,24: 1196~1202.
  • [5]Wu RQ,Xu YX,Song XH,Chen LJ,Meng XJ.Adhesion molecule and proinflammatory cytokine gene expression in hepatic sinusoidal endothelial cells following cecal ligation and puncture.World J Gastroenterol,2001,7:128~130.
  • [6]Ge YM,Ezzell RM,Clark BD,Loiselle PM,Amato SF,Warren HS.Relationship of tissue and cellular interleukin-1 and lipopolysaccharide after endotoxemia and bacteremia.J Infect Dis,1997,176:1313~1321.
  • [7]Cunningham ME,Shaw TA,Bernstein LH,Tinghitella TJ,Claus RE,Brogan DA,McMillen MA.Cholecystokinin-stimulated monocytes produce inflammatory cytokines and eicosanoids.Am J Gastroenterol,1995,90: 621~626.
  • [8]Lieb K,Fiebich BL,Grawitzm MB,Hull M,Berger M.Effect of substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes: a re-examination.J Neuroimmunol,1996,67: 77~81.
  • [9]Meng AH (孟爱宏),Ling YL (凌亦凌),Wang DH (王殿华),Gu ZY (谷振勇),Li SJ (李淑瑾),Zhu TN (朱铁年).Cholecystokinin-octapeptide alleviates tumor necrosis factor-alpha induced changes in rabbit pulmonary arterial reactivity and injuries of endothelium in vitro.Acta Physiol Sin (生理学报),2000;52(6):502~506 (Chinese,English abstract).
  • [10]Ottervein LE,Bach FH,Alam J,Soares,Lu HT,Wysk M,Davis RJ,Flavell RA,Choi AMK.Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway.Nat Med,2000,6:422~428.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615