Effect of interleukin-2 on intracellular calcium transients in rat ventricular myocytes

( views:, downloads: )
Journal Title:
Volume 53, Issue 06, 2001
Key Word:


  • [1]Gulick T, Chung MK, Pieper SJ et al. Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness. Proc Natl Acad Sci USA, 1989,86(17):6753~6757.
  • [2]Oral H, Dorn GW 2nd, Mann DL. Sphingosine mediates the immediate negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian cardiac myocyte. J Biol Chem, 1997,272(8):4836~4842.
  • [3]Finkel MS, Oddis CV, Jacob TD et al. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science, 1992,257(6):387~389.
  • [4]Sterin Borda L, Leiros CP, Borda ES et al. Effects of IL-2 on the myocardium. Participation of the sympathetic system. J Mol Cardiol, 1996,28(12):2457~2465.
  • [5]Kay NE, Morley JE, Allen JI. Interaction between endogenous opioids and IL-2 on PHA-stimulated human lymphocytes. Immunology, 1990,70(4):485~491.
  • [6]Jiang CL (蒋春雷), Xu D (徐荻), You ZD (由振东) et al. Possible mechanism of the analgesic effect of interleukin-2 in central nervous system. Acta Physiol Sin (生理学报), 1996,48(3):243~248 (Chinese, English abstract) .
  • [7]Farmer BB, Mancina M, Williams ES et al. Isolation of calcium tolerance myocytes from adult rat hearts: review of the literature and description of a method. Life Sci, 1983,33(1):1~18.
  • [8]Ventura C, Capogrossi MC, Spurgeon HA et al. Kappa-opioid peptide receptor stimulation increases cytosolic pH and myofilament responsiveness to Ca2+ in cardiac myocytes. Am J Physiol, 1991,261(5 Pt 2):H1671~H1674.
  • [9]Kanaya N, Zakhary DR, Murray PA et al. Thiopental alters contraction, intracellular Ca2+, and pH in rat ventricular myocytes. Anesthesiology, 1998,89(1):202~214.
  • [10]Pepe S, Xiao RP, Hohl C et al. ‘Cross talk' between opioid peptide and adrenergic receptor signaling in isolated rat heart. Circulation, 1997,95(8):2122~2129.
  • [11]Wu S, Li HY, Wong TM. Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte. Involvement of kappa-opioid receptor. Circ Res, 1999,84(12):1388~1395.
  • [12]Xie LH, Horie M, James AF et al. Endothelin-1 inhibits L-type Ca currents enhanced by isoproterenol in guinea pig ventricular myocytes. Pfluger Arch, 1996,431(4):533~539.
  • [13]Seino Y, Ikeda U, Minezaki KK et al. Expression of cytokine-induced neutrophil chemoattractant in rat cardiac myocytes. J Mol Cell Cardiol, 1995,27(9):2043~2051.
  • [14]Bian JS, Zhang WM, Xia Q et al. Phospholipase C inhibitors attenuate arrhythmias induced by κ-receptor stimulation in the isolated rat heart. J Mol Cell Cardiol, 1998,30(10):2103~2110.
  • [15]Tai KK, Jin WQ, Chan TKY et al. Characterization of [3H] U69593 binding sites in the rat heart by receptor binding assays. J Mol Cell Cardiol, 1991,23(11):1297~1302.
  • [16]Li ZY, Yang HH, Huang JQ et al. Competition of opioid receptor by human recombinant interleukin-2. J Interferon Res, 1990,10(Suppl.1):s141.
  • [17]Sheng JZ, Wong NS, Wang HX et al. Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+]i in myocytes. Am J Physiol, 1997,272(2 Pt 1):C560~C564.
  • [18]Wong TM, Sheng JZ, Wong NS et al. Signal transduction in the cardiac κ-receptor. Biol Signals, 1995,4(3):174~178.
  • [19]Gesbert F, Delespine Carmagnat M, Bertoglio J. Recent advances in the understanding of interleukin-2 signal transduction. J Clin Immunol, 1998,18(5):307~320.
  • [20]Weisensee D, Bereiter HJ, Schoeppe W et al. Effects of cytokines on the contractility of cultured cardiac myocytes. Int J Immunopharmacol, 1993,15(5):581~587.
  • [21]Wang LL (王琳琳), Lin GH (林国华), Chen YY (陈莹莹) et al. Nitric oxide mediated the inhibitory effects of interleukin-2 on the isolated ventricular papillary muscle and cultured neonatal rat cardiomyocyte. J Zhejiang Univ (浙江大学学报), (修改稿) (Chinese, English abstract).
  • [22]Xia Q (夏强), Lu Y (陆源), Shen YL (沈岳良) et al. Increased ventricular vulnerability by κ-opioid agonist and its mechanism. Chin Pharmacol Bull (中国药理学通报), 1995,11(6):464~467 (Chinese, English abstract).
  • [23]Micol JA, Laorden ML. Interaction of U-50,488H with calcium channel agonists and antagonists in different cardiac tissues. J Auton Pharmacol, 1992,12(6):437~444.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn