Antiarrhythmic and antioxidative effects of intermittent hypoxia exposure on rat myocardium

( views:, downloads: )
ZHONG Ning()
ZHU Hai-Feng()
ZHOU Zhao-Nian()
Journal Title:
Volume 52, Issue 02, 2000
Key Word:


  • [1]Meerson FZ. Adaptation to intermittent hypoxia and its use for protecting the stress and ischemic damage. In Meerson FZ, ed. Adaptative Protection of the Heart: Protecting Against Stress and Ischemic Damage. Florida: CRC Press, 1991, 249~284.
  • [2]Cerati D, Schwartz PJ. Single cardiac vagal fiber activity, acute myocardial ischemia, and risk for sudden death. Circ Res, 1991, 69: 1389~1401.
  • [3]Walker MJA, Curtis MJ, Hearse DJ et al. The Lambeth conventions: guidelines for the study of arrhythmias in ischemia, infarction, and reperfusion. Cardiovasc Res, 1988, 22: 447~455.
  • [4]Johnston KM, Macleod BA, Walker JA. Responses to lig~ation of a coronary artery in conscious rats and the actions of antiarrhythmics. Can J Physiol Pharmacol, 1983, 61: 1340~1353.
  • [5]Marklund S, Marklund G. Involvement of the superoxide anion radical in the antioxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem, 1974, 47: 469~474.
  • [6]Ohkawa H, Ohishi N, Yagi K et al. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem, 1979, 95: 351~358.
  • [7]Meerson FZ, Beloshitskii PV, Vorontsova Eia et al. Effects of adaptation to continuous and intermittent hypoxia on heart resistance to ischemic and reperfusion arrhythmias. Patol Fiziol Eksp Ter, 1989, May-Jun (3): 48~50.
  • [8]Zhuang JG, Zhou ZN. Protective Effects of intermittent hypoxia adaptation on myocardium and its mechanisms. Biol Signals Recept, 1999, 8: 316~322.
  • [9]Jeroudi MO, Hartley CJ, Bolli R et al. Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidant. Am J Cardiol, 1994, 73: 2B~7B.
  • [10]Chen M, Zhou ZN. Effects of hypoxia on myoglobin and antioxidant enzymes in rat myocardium. Exp Clin Cardiol, 1997, 2: 179~183.
  • [11]Tan DX, Manchester LC, Reiter RJ et al. Ischemia/reperfusion-induced arrhythmias in the isolated rat heart:prevention by melatonin. J Pineal Res, 1998, 25: 184~91.
  • [12]Wang XL. Pharmacology of ion channels and antiarrhythmic drugs. In Chen WZ et al. eds. Progress of Cardiovascular Pharmacology (1994~1995). Beijing: People's Health Publishing House, 1995, 77~89.
  • [13]Pei SX, Chen XJ, Si Ren BZ et al. Chronic mountain sickness in Tibet. Q J Med, 1989, 71 (266): 555~574.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615