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AN OBSERVATION ON THE POSSIBLE EXISTANCE OF SOME INFORMATION TRANSMISSION BETWEEN SENSORY NERVE ENDINGS OF RAT
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- Author:
- No author available
- Journal Title:
- ACTA PHYSIOLOGICA SINICA
- Issue:
- 6
- DOI:
- 10.3321/j.issn:0371-0874.1997.06.006
- Key Word:
- 感觉神经末梢;信息传递;大鼠
Abstract： 实验切断麻醉大鼠一侧T5～L1脊神经背部皮支的中枢端,用50 Hz,0.2ms,总时间为2 s的方波逆行刺激其中一皮支的外周端,记录其相邻皮支的电活动.结果发现刺激停止后25 s内被记录皮支的放电迅速增加,继而逐渐恢复到刺激前的水平;414个序列实验结果的累积时程分析表明:被记录皮支的放电频率在刺激停止后的第2秒达最大值,并持续3 s,从第5秒开始逐渐下降,第25秒及以后恢复到刺激前的水平;放电频率的增加量与刺激前被记录皮支的自发放电频率呈直线正相关,且在一定程度上与刺激序列数相关;相同条件的单脉冲刺激未能在被记录皮支上诱发出放电频率增加或记录到复合动作电位.实验还用夹伤被刺激皮支的方法排除了电流扩散引起相邻皮支放电增加的可能.结果提示:初级感觉神经外周末梢间可以进行化学性信息传递.
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