STUDIES ON DESENSITIZATION OF GABAB RECEPTOR COUPLED ADENYLATE CYCLASE

( views:, downloads: )
Author:
YU ZAI-FANG()
CHENG GUAN-JUN()
HU Ben-rong()
Journal Title:
ACTA PHYSIOLOGICA SINICA
Issue:
Volume 49, Issue 01, 1997
DOI:
Key Word:

Abstract:

  • [1]Sibley DR, Benovic JL, Caron MG, et al. Regulation of transmembrane signaling by receptor phosphorylation. Cell,1987,48:913~922
  • [2]Taniyama K, Niwa M, Kataoka Y,et al. Activation of protein kinase C suppresses the gamma-aminobutyric acidB receptor-mediated inhibition of the vesicular release of noradrenaline and acetycholine. J Neurochem,1992,58: 1239~ 1245
  • [3]Kamatchi GL,Ticku MK. GABAB receptor activation inhibits Ca2+ activated 86Rb efflux in cultured spinal cord neurons via G-proteinmechanism. Brain Res, 1990,506:181 ~ 186
  • [4]Enna SJ,Karbon EW. GABAB receptors and transmitter-stimulated cAMP accumulation in rat brain. Neuropharmacology, 1994,23: 821 ~822
  • [5]Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the folin phenol reagent. J Biol Chem, 1951,193:265~275
  • [6]Kelleher DJ, Pessin JE, Ruoho AE, et al. Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the β-adrenergic receptor in turkey erythrocytes. Proc Natl Acad Sci USA, 1984,81: 4316 ~ 4320
  • [7]Ohm TG, Bohl J, Lemmer B. Reduced basal and stimulated(isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimers disease correlated with histophological changes. Brain Res, 1990, 540: 229 ~ 236
  • [8]Bowery NG, Hill DR, Hudson AL. Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes. Br J Pharmacol, 1983,73:191 ~ 206
  • [9]Hahner I, McQuikin S,Harris RA. Cerebellar GABAB receptors modulate function of GABAA receptors.FASEB J, 1990,5: 2466~ 2472
  • [10]Milligan G,Green A. Agonists control of G-protein levels. TIPS,1990,12:207~213
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn